Synthesis and Characterization of the First Potent Inhibitor of Yapsin 1 IMPLICATIONS FOR THE STUDY OF YAPSIN-LIKE ENZYMES*
Cawley NX, Chino M, Maldonado A, Rodriguez YM, Loh YP, Ellman JA. Synthesis and Characterization of the First Potent Inhibitor of Yapsin 1 IMPLICATIONS FOR THE STUDY OF YAPSIN-LIKE ENZYMES*. Journal Of Biological Chemistry 2002, 278: 5523-5530. PMID: 12468548, DOI: 10.1074/jbc.m207230200.Peer-Reviewed Original ResearchConceptsYapsin 1Aspartyl proteaseN-terminal amino acid sequence analysisYeast expression systemAmino acid sequence analysisSecreted aspartyl proteaseAcid sequence analysisPotent peptidic inhibitorsSingle-step purificationBasic residuesExpression systemSequence analysisApparent homogeneityPeptidic inhibitorsHuman pathogensPeptide sequencesNonmammalian sourcesFirst potent inhibitorPotent inhibitorProteaseEnzymeCandida albicansSequenceInhibitorsPurification
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply