Fibrolamellar carcinoma of the liver exhibits immunohistochemical evidence of both hepatocyte and bile duct differentiation
Ward S, Huang J, Tickoo S, Thung S, Ladanyi M, Klimstra D. Fibrolamellar carcinoma of the liver exhibits immunohistochemical evidence of both hepatocyte and bile duct differentiation. Modern Pathology 2010, 23: 1180-1190. PMID: 20495535, DOI: 10.1038/modpathol.2010.105.Peer-Reviewed Original ResearchConceptsFibrolamellar carcinoma casesCases of fibrolamellar carcinomaEpithelial membrane antigenCarcinoma casesHepatocellular carcinoma casesFibrolamellar carcinomaBile duct differentiationHepatocellular carcinomaCytokeratin 7In situ hybridizationNeuroendocrine differentiationMembrane antigenGlypican-3Duct differentiationEvidence of neuroendocrine differentiationCanalicular staining patternPrimary liver neoplasmAlbumin mRNANeuroendocrine markersImmunohistochemical profileHepatocellular differentiationYounger patientsImmunohistochemical markersTumor typesViral hepatitis
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