2025
Spike Ripples: Hidden Clues to the Mystery of the Epileptogenic Zone
Quraishi I. Spike Ripples: Hidden Clues to the Mystery of the Epileptogenic Zone. Epilepsy Currents 2025, 25: 101-103. PMID: 39780979, PMCID: PMC11705290, DOI: 10.1177/15357597241306610.Commentaries, Editorials and LettersSpike ripplesFast ripplesInterictal biomarkerSurgical resectionEpileptogenic zoneMulticentre cohortResection volumePersistent seizuresEpileptogenic tissueILA-1Ripple rateImproved biomarkersSubjective outcomesEpileptiform spikesProportion of spikesResectionSubdural electrodesBiomarkersEpileptogenicityHigh-frequency oscillationsOutcomesILASubjectsIntracranial electroencephalogramTissue
2014
The spatial and signal characteristics of physiologic high frequency oscillations
Alkawadri R, Gaspard N, Goncharova II, Spencer DD, Gerrard JL, Zaveri H, Duckrow RB, Blumenfeld H, Hirsch LJ. The spatial and signal characteristics of physiologic high frequency oscillations. Epilepsia 2014, 55: 1986-1995. PMID: 25470216, PMCID: PMC5123742, DOI: 10.1111/epi.12851.Peer-Reviewed Original ResearchConceptsPhysiologic high-frequency oscillationsSeizure onsetEpileptic networkNon-rapid eye movement sleepComprehensive Epilepsy CenterMesial temporal structuresEye movement sleepHigh-frequency oscillationsHighest HFO ratesFirst seizureInvasive evaluationEpilepsy centersIntracranial evaluationMovement sleepPerirolandic regionEpileptiform dischargesParietooccipital regionOccipital lobeEpileptic sitesPatientsNonepileptic regionsPhysiologic eventsFast ripplesHFO ratesLonger duration
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