2023
A Novel Dual-Function Nitric Oxide Donor Therapy for Preeclampsia—A Proof-of-Principle Study in a Murine Model
Pintye D, Sziva R, Biwer L, Karreci E, Jacas S, Mastyugin M, Török M, Young B, Jagtap P, Southan G, Jaffe I, Zsengellér Z. A Novel Dual-Function Nitric Oxide Donor Therapy for Preeclampsia—A Proof-of-Principle Study in a Murine Model. Antioxidants 2023, 12: 2036. PMID: 38136156, PMCID: PMC10741224, DOI: 10.3390/antiox12122036.Peer-Reviewed Original ResearchBlood pressureOxidative stressNitric oxide donor therapyPlasma cystatin C.Plasma nitrate levelsHealthy female miceModel of preeclampsiaNitric oxide bioavailabilityEx vivo treatmentPotential therapeutic effectsReduced oxidative stressNovel therapeutic agentsDays of treatmentAnti-angiogenic responseDonor therapyPlacental damageReduced hypertensionHypertensive disordersSubstantial morbidityFetal pathophysiologyResistance vesselsGlomerular endotheliosisPE symptomsVascular disordersFemale mice
1987
B lymphocyte reconstitution after human bone marrow transplantation. Leu-1 antigen defines a distinct population of B lymphocytes.
Antin JH, Ault KA, Rappeport JM, Smith BR. B lymphocyte reconstitution after human bone marrow transplantation. Leu-1 antigen defines a distinct population of B lymphocytes. Journal Of Clinical Investigation 1987, 80: 325-332. PMID: 3112184, PMCID: PMC442241, DOI: 10.1172/jci113076.Peer-Reviewed Original ResearchConceptsLeu-1B cellsMarrow transplantationHuman bone marrow transplantationEffect of GVHDHuman marrow transplantationBone marrow transplantationEx vivo treatmentInterleukin-2 receptorB lymphocyte reconstitutionSeparate B cell lineageNormal B cellsB-cell lineageAcute GVHDChronic graftHost diseaseLymphocyte reconstitutionDonor originVivo treatmentB lymphocytesMultivariate analysisStages of differentiationGVHDTransplantationMarrow
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