The oncocytic subtype is genetically distinct from other pancreatic intraductal papillary mucinous neoplasm subtypes
Basturk O, Tan M, Bhanot U, Allen P, Adsay V, Scott S, Shah R, Berger M, Askan G, Dikoglu E, Jobanputra V, Wrzeszczynski K, Sigel C, Iacobuzio-Donahue C, Klimstra D. The oncocytic subtype is genetically distinct from other pancreatic intraductal papillary mucinous neoplasm subtypes. Modern Pathology 2016, 29: 1058-1069. PMID: 27282351, PMCID: PMC5524210, DOI: 10.1038/modpathol.2016.98.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkers, TumorChromograninsDNA Mutational AnalysisDNA-Binding ProteinsFemaleGene Expression ProfilingGenetic Predisposition to DiseaseGTP-Binding Protein alpha Subunits, GsHigh-Throughput Nucleotide SequencingHumansMaleMiddle AgedMutationNeoplasms, Cystic, Mucinous, and SerousOncogene ProteinsOxyphil CellsPancreatic NeoplasmsPhenotypeProto-Oncogene Proteins p21(ras)Tumor Suppressor Protein p53Ubiquitin-Protein LigasesWhole Genome SequencingConceptsIntraductal papillary mucinous neoplasmIntraductal papillary mucinous neoplasm subtypesPapillary mucinous neoplasmMucinous neoplasmsOncocytic epitheliumSubtyping intraductal papillary mucinous neoplasmsOncocytic subtypesNext-generation sequencingWorld Health OrganizationIntraductal oncocytic papillary neoplasmParaffin-embedded specimensCopy number alterationsIdentification of sequence mutationsCancer-associated genesOncocytic cytoplasmGNAS mutationsPIK3R1 mutationsFresh-frozen specimensHealth OrganizationPapillary neoplasmERBB4 geneMolecular alterationsFormalin-FixedNeoplasmsRNF43 mutations
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply