2024
Age-dependent pathogenic profiles of enterotoxigenic Escherichia coli diarrhea in Bangladesh
Akhtar M, Begum Y, Isfat Ara Rahman S, Afrad M, Parvin N, Akter A, Tauheed I, Amin M, Ryan E, Khan A, Chowdhury F, Bhuiyan T, Qadri F. Age-dependent pathogenic profiles of enterotoxigenic Escherichia coli diarrhea in Bangladesh. Frontiers In Public Health 2024, 12: 1484162. PMID: 39726651, PMCID: PMC11669683, DOI: 10.3389/fpubh.2024.1484162.Peer-Reviewed Original ResearchEnterotoxigenic Escherichia coliETEC infectionColonization factorsEnterotoxigenic Escherichia coli strainsEnterotoxigenic Escherichia coli infectionEnterotoxigenic Escherichia coli diarrheaETEC casesClinical manifestationsETEC-associated diarrheaHost-pathogen interactionsAge groupsPrevalence of antimicrobial resistanceDevelopment of targeted vaccinesETEC antigensETEC diarrheaVirulence factorsYears age groupDiarrheal patientsHospital surveillance dataToxin typesAge-specific distributionChildren Aged 0Pediatric casesAntimicrobial resistanceCFA/I
2023
The indelible toll of enteric pathogens: Prevalence, clinical characterization, and seasonal trends in patients with acute community-acquired diarrhea in disenfranchised communities
Osman M, Kassem I, Dabboussi F, Cummings K, Hamze M. The indelible toll of enteric pathogens: Prevalence, clinical characterization, and seasonal trends in patients with acute community-acquired diarrhea in disenfranchised communities. PLOS ONE 2023, 18: e0282844. PMID: 36913372, PMCID: PMC10010529, DOI: 10.1371/journal.pone.0282844.Peer-Reviewed Original ResearchConceptsEnteropathogenic E. coliEnteroaggregative Escherichia coliEnterotoxigenic E. coliEnteric pathogensCross-sectional community-based studyAcute community-acquired diarrheaMultivariable logistic regression modelCommon parasitic agentsCommunity-acquired diarrheaCommunity-based studyPublic health challengeLogistic regression modelsGII infectionsAcute diarrheaMiddle-income countriesGastrointestinal PanelDiarrheic patientsEnteric infectionsOverall prevalenceRisk factorsStool samplesClinical characterizationETEC infectionDiarrheal diseaseEtiologic agent
2016
Individual-specific changes in the human gut microbiota after challenge with enterotoxigenic Escherichia coli and subsequent ciprofloxacin treatment
Pop M, Paulson J, Chakraborty S, Astrovskaya I, Lindsay B, Li S, Bravo H, Harro C, Parkhill J, Walker A, Walker R, Sack D, Stine O. Individual-specific changes in the human gut microbiota after challenge with enterotoxigenic Escherichia coli and subsequent ciprofloxacin treatment. BMC Genomics 2016, 17: 440. PMID: 27277524, PMCID: PMC4898365, DOI: 10.1186/s12864-016-2777-0.Peer-Reviewed Original ResearchConceptsGene sequencesBackgroundEnterotoxigenic Escherichia coliHuman gut microbiotaRRNA gene sequencesEnterotoxigenic Escherichia coliHuman intestinal microbiotaFecal E. coliCiprofloxacin treatmentETEC infectionETEC diarrheaRibosomal RNAGut microbiotaFecal microbiotaIntestinal microbiotaE. coliMicrobiotaMonthly follow-up visitsCompared to variationsETECFollow-up visitQuantitative PCRHuman challenge studiesCiprofloxacinQuantitative culturesSequence
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