Rap1 maintains adhesion between cells to affect Egfr signaling and planar cell polarity in Drosophila
O'Keefe D, Gonzalez-Niño E, Burnett M, Dylla L, Lambeth S, Licon E, Amesoli C, Edgar B, Curtiss J. Rap1 maintains adhesion between cells to affect Egfr signaling and planar cell polarity in Drosophila. Developmental Biology 2009, 333: 143-160. PMID: 19576205, PMCID: PMC2730837, DOI: 10.1016/j.ydbio.2009.06.032.Peer-Reviewed Original ResearchConceptsPlanar cell polarityCell polarityMutant tissueEGFR SignalingCell fate specificationEpithelial cell shapeOmmatidial rotationMutant cellsGTPase Rap1Cell motilityFate specificationSignal transductionRap1Cell shapeCell signalingJunctional localizationRap1 inactivationWing veinsCell adhesionDevelopmental processesHair alignmentCell typesFunctional readoutTissue differentiationDevelopmental context
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