2022
Chapter 8 Exploring the role of protein quality control in aging and age-associated neurodegenerative diseases
Gogia N, Olmos V, Haidery F, Luttik K, Tejwani L, Lim J. Chapter 8 Exploring the role of protein quality control in aging and age-associated neurodegenerative diseases. 2022, 139-171. DOI: 10.1016/b978-0-323-90235-9.00012-4.ChaptersPQC systemAge-associated neurodegenerative diseasesAge-related neurodegenerative diseasesProtein quality control systemCell deathNeurodegenerative diseasesProtein quality controlHallmark of agingAlters cellular functionCellular proteomeCellular functionsProtein misfoldingQuality control systemCellular agingBiological processesPostmitotic natureNeuronal cell deathProteinDisease symptomsEfficient clearanceTherapeutic targetCellsDisease conditionsNervous system tissueEffective therapeutics
2019
Astrocyte senescence: Evidence and significance
Cohen J, Torres C. Astrocyte senescence: Evidence and significance. Aging Cell 2019, 18: e12937. PMID: 30815970, PMCID: PMC6516680, DOI: 10.1111/acel.12937.Peer-Reviewed Original ResearchConceptsCentral nervous systemNeurodegenerative diseasesNeurodegenerative disordersAge-associated neurodegenerative diseasesCellular senescenceProgression of neurodegenerative diseasesAge-related neurodegenerative diseasesCentral nervous system dysfunctionLoss of astrocyte functionMechanisms of agingPhysiological roleNeuroinflammatory functionsIn vitro characterizationAging BrainCognitive decline
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