A Novel Role for the AAA ATPase Spastin as a HOXA10 Transcriptional Corepressor in Ishikawa Endometrial Cells
Daftary GS, Tetrault AM, Jorgensen EM, Sarno J, Taylor HS. A Novel Role for the AAA ATPase Spastin as a HOXA10 Transcriptional Corepressor in Ishikawa Endometrial Cells. Endocrinology 2011, 25: 1539-1549. PMID: 21757506, PMCID: PMC3165913, DOI: 10.1210/me.2011-0001.Peer-Reviewed Original ResearchConceptsEmpty spiracles homeobox 2Novel roleNuclear localization signal sequenceHoxA10 target geneEMX2 expressionDrosophila empty spiraclesCorepressor complexImplantation biologyTranscriptional regulationTranscriptional corepressorTranscriptional complexChromatin immunoprecipitationHuman orthologEndometrial expressionImplantation rateSignal sequenceTranscription factorsEndometrial cellsEmpty spiraclesEmbryo receptivityIshikawa cellsNovel functionTarget genesHomeobox A10Embryo implantation
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