2025
Case Report: jaundice in the young: the complexity of rare diseases beyond cholangiopathies
Guglielmo S, Pasin F, Biolo M, Mescoli C, Vio S, Fabris L, Simioni P. Case Report: jaundice in the young: the complexity of rare diseases beyond cholangiopathies. Frontiers In Gastroenterology 2025, 4: 1579928. DOI: 10.3389/fgstr.2025.1579928.Peer-Reviewed Original ResearchAutoimmune hemolytic anemiaInflammatory bowel diseaseSerum IgG4 levelsAutoimmune pancreatitisCorticosteroid therapyIgG4 levelsClinical presentationAssociated with elevated serum IgG4 levelsDiagnosis of type 2 AIPComplication of autoimmune pancreatitisSuspicion of autoimmune pancreatitisElevated serum IgG4 levelsRemission of jaundiceType 2 AIPAssociated with inflammatory bowel diseaseBile duct dilatationPositive Coombs testDiagnosis of Crohn's diseaseMild weight lossPancreato-biliary diseasesPresentation of diseasePale stoolsAbdominal painClinical responseUnnecessary surgery
2010
Use of immunohistochemistry for IgG4 in the distinction of autoimmune pancreatitis from peritumoral pancreatitis
Dhall D, Suriawinata A, Tang L, Shia J, Klimstra D. Use of immunohistochemistry for IgG4 in the distinction of autoimmune pancreatitis from peritumoral pancreatitis. Human Pathology 2010, 41: 643-652. PMID: 20149413, DOI: 10.1016/j.humpath.2009.10.019.Peer-Reviewed Original ResearchConceptsSerum IgG4 levelsIgG4-positive cellsAutoimmune pancreatitisPeritumoral pancreatitisIgG4 levelsIgG4 stainingEpithelial lesionsPancreatitis casesPancreatic cancerElevated serum IgG4 levelsCase of autoimmune pancreatitisDiagnosing autoimmune pancreatitisDense stainingPancreatic head massGranulocytic epithelial lesionsPositive plasma cellsAreas of acute inflammationUsefulness of immunohistochemistryPancreatic ductal adenocarcinomaIgG4 immunohistochemistryPancreatic resectionSclerosing pancreatitisPancreatic adenocarcinomaPancreatic massDiagnostic dilemma
2004
Lymphoplasmacytic sclerosing (autoimmune) pancreatitis
Klimstra D, Adsay N. Lymphoplasmacytic sclerosing (autoimmune) pancreatitis. Seminars In Diagnostic Pathology 2004, 21: 237-246. PMID: 16273942, DOI: 10.1053/j.semdp.2005.07.004.Peer-Reviewed Original ResearchConceptsLymphoplasmacytic sclerosing pancreatitisPancreatic carcinomaFibroinflammatory lesionsChronic pancreatitisAutoimmune diseasesDuct-destructive chronic pancreatitisElevated serum IgG4 levelsResponse to steroid therapyAssociated with other autoimmune diseasesManifestations of autoimmune diseasePeriductal lymphoplasmacytic inflammationSerum IgG4 levelsBile duct strictureCases of lymphoplasmacytic sclerosing pancreatitisMiddle-aged patientsTumor-like massHistologically distinct typesPreoperative diagnostic testsObliterative venulitisSteroid therapySurgical resectionBiliary involvementIgG4 levelsResected casesDuct strictures
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