2021
Sperm deoxyribonucleic acid fragmentation: predictors, fertility outcomes, and assays among infertile males
Rios JS, Coward RM, Hansen KR, Barnhart KT, Cedars MI, Legro RS, Diamond MP, Krawetz SA, Usadi R, Baker VL, Sun F, Wild R, Smith JF, Santoro N, Zhang H, Steiner AZ. Sperm deoxyribonucleic acid fragmentation: predictors, fertility outcomes, and assays among infertile males. F&S Reports 2021, 2: 282-288. PMID: 34553152, PMCID: PMC8441563, DOI: 10.1016/j.xfre.2021.06.003.Peer-Reviewed Original ResearchPregnancy outcomesInfertile menSperm deoxyribonucleic acid fragmentationMultivariable linear regression modelsTransferase-mediated dUTP nickDeoxyribonucleic acid fragmentationLower total sperm motilityOvarian stimulationBaseline visitFertility centerTubal patencyIntrauterine inseminationLive birthsFertility outcomesInfertile malesSecondary analysisOlder ageDUTP nickFemale partnersSpearman correlationSperm concentrationSignificant predictorsTotal sperm motilityModest correlationMen
2004
Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin
Takeuchi S, Zhang W, Wakamatsu K, Ito S, Hearing VJ, Kraemer KH, Brash DE. Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin. Proceedings Of The National Academy Of Sciences Of The United States Of America 2004, 101: 15076-15081. PMID: 15477596, PMCID: PMC524044, DOI: 10.1073/pnas.0403994101.Peer-Reviewed Original ResearchConceptsYellow miceTerminal deoxynucleotidyltransferase-mediated dUTP nickTUNEL-positive cellsActive caspase-3Sunburn cellsPositive cellsBlack miceSkin cancerCongenic miceMurine skinDUTP nickDNA strand breaksMiceEpidermal sheetsHair folliclesAbility of melaninCaspase-3Sensitivity of individualsApoptosisLesionsUVA radiationRed hairCell deathHair shaftSunlight UV radiation
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