Multifunctional molecule ERp57: From cancer to neurodegenerative diseases
Hettinghouse A, Liu R, Liu C. Multifunctional molecule ERp57: From cancer to neurodegenerative diseases. Pharmacology & Therapeutics 2017, 181: 34-48. PMID: 28723413, PMCID: PMC5743601, DOI: 10.1016/j.pharmthera.2017.07.011.Peer-Reviewed Original ResearchConceptsProtein disulfide isomerase gene familyMultiple cellular localizationsEndoplasmic reticulum localizationDiverse pathological statesGene familyERp57 functionsProtein familyPDI familySubcellular compartmentsPhysiological processesCellular localizationMultifunctional memberERp57Aberrant functionalityNeurodegenerative diseasesTherapeutic developmentPathological statesFamilyLocalizationIsomeraseRedox activityAvailable knowledgeNumerous studiesHostExpression
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