2020
Sequencing and Structure Probing of Long RNAs Using MarathonRT: A Next-Generation Reverse Transcriptase
Guo LT, Adams RL, Wan H, Huston NC, Potapova O, Olson S, Gallardo CM, Graveley BR, Torbett BE, Pyle AM. Sequencing and Structure Probing of Long RNAs Using MarathonRT: A Next-Generation Reverse Transcriptase. Journal Of Molecular Biology 2020, 432: 3338-3352. PMID: 32259542, PMCID: PMC7556701, DOI: 10.1016/j.jmb.2020.03.022.Peer-Reviewed Original ResearchConceptsLong RNA moleculesLong RNAsRNA moleculesRNA base modificationsGroup II intronsMutational profilingTranscriptome compositionRNA metabolismRNA researchBase modificationsPrimer extensionTool enzymeDiverse aspectsMixed populationEnzymeReverse transcriptionRNAStructural complexityReverse transcriptaseProfilingTranscriptase enzymeIntronsTranscription
2016
A novel small molecule that disrupts a key event during the oocyte-to-embryo transition in C. elegans
Weicksel SE, Mahadav A, Moyle M, Cipriani PG, Kudron M, Pincus Z, Bahmanyar S, Abriola L, Merkel J, Gutwein M, Fernandez AG, Piano F, Gunsalus KC, Reinke V. A novel small molecule that disrupts a key event during the oocyte-to-embryo transition in C. elegans. Development 2016, 143: 3540-3548. PMID: 27510972, PMCID: PMC5087616, DOI: 10.1242/dev.140046.Peer-Reviewed Original ResearchConceptsEmbryo transitionProtein traffickingEarly embryonic eventsCandidate target genesComplex cellular eventsSmall-molecule screenCaenorhabditis elegansInviable embryosC. elegansEmbryonic lethalityMore key componentsEarly embryogenesisTranscription factorsEarly embryosEmbryonic eventsTarget genesCellular eventsSpecies specificityEggshell integrityNovel small moleculesElegansRemarkable specificityKey eventsOsmotic sensitivityDiverse aspects
2004
Functions of Rab GTPases in organelle biogenesis
Burd C, Collins R. Functions of Rab GTPases in organelle biogenesis. Topics In Current Genetics 2004, 10: 65-88. DOI: 10.1007/b97781.Peer-Reviewed Original ResearchRab GTPasesSpecific effector proteinsVesicle tetheringOrganelle biogenesisMembrane traffickingCargo sortingEffector proteinsEndocytic organellesGTP bindingOrganelle transportGTPasesConformational changesBiogenesisDiverse aspectsRabRecent progressOrganellesTraffickingProteinTetheringBindingSortingFusion
1993
Expression and regulation of mammalian K+ channel genes
Perney T, Kaczmarek L. Expression and regulation of mammalian K+ channel genes. Seminars In Neuroscience 1993, 5: 135-145. DOI: 10.1016/s1044-5765(05)80008-9.Peer-Reviewed Original ResearchChannel gene expressionGene expressionChannel genesRegulation of mammalianParticular spatial domainSpecific cell typesDifferent environmental stimuliCellular functionsChannel proteinsCell typesEnvironmental stimuliCell occurDiverse aspectsSuch regulationGenesRegulationChannel expressionGrowth factorExpressionExcitable tissuesLongterm changesCellsSuperfamilyMammalianProtein
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