Mother Centriole Distal Appendages Mediate Centrosome Docking at the Immunological Synapse and Reveal Mechanistic Parallels with Ciliogenesis
Stinchcombe J, Randzavola L, Angus K, Mantell J, Verkade P, Griffiths G. Mother Centriole Distal Appendages Mediate Centrosome Docking at the Immunological Synapse and Reveal Mechanistic Parallels with Ciliogenesis. Current Biology 2015, 25: 3239-3244. PMID: 26670998, PMCID: PMC4691242, DOI: 10.1016/j.cub.2015.10.028.Peer-Reviewed Original ResearchConceptsCilia formationSmall interfering RNACentrosome dockingCentrosome polarizationMother centriolePlasma membraneImmunological synapseBasal body dockingDistal appendage proteinsCytotoxic T lymphocytesPrimary cilia formationAppendage proteinsSecretory lysosomesPolarized secretionDistal appendagesCentriole pairCell cycleCiliogenesisCentrosomeMechanistic parallelsMembrane contactSynapse formationPolarized releaseCentriolesSynapse
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