Different Evolutionary Histories of the Two Classical Class I Genes BF1 and BF2 Illustrate Drift and Selection within the Stable MHC Haplotypes of Chickens
Shaw I, Powell T, Marston D, Baker K, van Hateren A, Riegert P, Wiles M, Milne S, Beck S, Kaufman J. Different Evolutionary Histories of the Two Classical Class I Genes BF1 and BF2 Illustrate Drift and Selection within the Stable MHC Haplotypes of Chickens. The Journal Of Immunology 2007, 178: 5744-5752. PMID: 17442958, DOI: 10.4049/jimmunol.178.9.5744.Peer-Reviewed Original ResearchConceptsClass I genesI geneChicken MHCChicken MHC haplotypesResistance to infectious pathogensLong-distance PCRMHC haplotypesPatterns of descentGenome organizationBF2 genesEvolutionary historyClass II BExpressed genesSite deletionHaplotypesNeutral changesB12 haplotypeGenesDendrogramWell-expressedChickenInfectious pathogensBF1Response to vaccinationClass I molecules
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