Cellular Activity of New Small Molecule Protein Arginine Deiminase 3 (PAD3) Inhibitors
Jamali H, Khan HA, Tjin CC, Ellman JA. Cellular Activity of New Small Molecule Protein Arginine Deiminase 3 (PAD3) Inhibitors. ACS Medicinal Chemistry Letters 2016, 7: 847-851. PMID: 27660689, PMCID: PMC5018872, DOI: 10.1021/acsmedchemlett.6b00215.Peer-Reviewed Original ResearchProtein arginine deiminasesThapsigargin-induced cell deathPost-translational deiminationHEK293T cellsArginine side chainHuman disease statesInhibitor 2Cellular activitiesCell deathPAD isozymesArginine deiminasesCell growthPAD activityPAD3Representative inhibitorsDisease statesNeurodegenerative responseSide chainsInhibitorsDeiminationApoptosisIsozymesActivityFirst timeCell activity
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