2024
Actively contractible and antibacterial hydrogel for accelerated wound healing
Ji Z, Wei T, Zhu J, Hu J, Xiao Z, Bai B, Lv X, Miao Y, Chen M, Wang C, Pan F, Yang Y, Li M, Chen Q. Actively contractible and antibacterial hydrogel for accelerated wound healing. Nano Research 2024, 17: 7394-7403. DOI: 10.1007/s12274-024-6674-6.Peer-Reviewed Original ResearchAdhesive hydrogelsPoly(N-isopropyl acrylamideAntibacterial hydrogelsFull-thickness skin defect modelMouse full-thickness skin defect modelSkin defect modelPNIPAAm networkEfficient antibacterial abilityMechanical propertiesThermoresponsive polymersHydrogelsDefect modelShrinkage abilityAntibacterial abilityImproved wound healing processTissue regenerationCatechol groupsAccelerated wound healingAntibacterial propertiesWound moistTissue adhesivesAntibacterial functionReactive oxygen speciesAdhesion abilityAdhesion
2013
Physiologic load-bearing characteristics of autografts, allografts, and polymer-based scaffolds in a critical sized segmental defect of long bone: an experimental study
Amorosa L, Lee C, Aydemir, Nizami S, Hsu A, Patel N, Gardner T, Navalgund A, Kim DG, Park S, Mao J, Lee F. Physiologic load-bearing characteristics of autografts, allografts, and polymer-based scaffolds in a critical sized segmental defect of long bone: an experimental study. International Journal Of Nanomedicine 2013, 8: 1637-1643. PMID: 23637532, PMCID: PMC3639117, DOI: 10.2147/ijn.s42855.Peer-Reviewed Original ResearchConceptsAddition of hMSCsPolymer-based scaffoldsLoad-bearing characteristicsPhysiologic cyclic loadingPhase angleCritical-sized segmental defectsScaffold alone groupViscous stiffnessCyclic loadingMechanical propertiesFemoral defect modelSized segmental defectsRat femoral defect modelHuman mesenchymal stem cellsMechanical simulationsScaffold groupDifferent biomechanical characteristicsEnhanced bone formationHigh phase anglesDefect modelBiomechanical characteristicsExperimental studyHost boneStiffnessDefect repair
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