2018
Impact of Health Insurance Status on Prostate Cancer Treatment Modality Selection in the United States
Bledsoe T, Park H, Rutter C, Aneja S, Nguyen PL, Yu J. Impact of Health Insurance Status on Prostate Cancer Treatment Modality Selection in the United States. American Journal Of Clinical Oncology 2018, 41: 1062-1068. PMID: 29521648, DOI: 10.1097/coc.0000000000000423.Peer-Reviewed Original ResearchTreatment modality selectionInsurance statusTreatment modalitiesProstate cancerPrivate insuranceProstate cancer treatment modalitiesMultivariable logistic regression analysisInvasive surgeryModality selectionCancer-directed treatmentD'Amico risk classificationTreatment modality choiceNational Cancer DatabaseLocalized prostate cancerPatient insurance statusExternal beam radiotherapyLogistic regression analysisHealth insurance statusStrongest predictorMen ages 18Cancer treatment modalitiesClinical factorsMultivariable analysisActive surveillanceCancer Database
2016
Racial/Ethnic Disparity in Treatment for Prostate Cancer: Does Cancer Severity Matter?
Moses K, Orom H, Brasel A, Gaddy J, Underwood W. Racial/Ethnic Disparity in Treatment for Prostate Cancer: Does Cancer Severity Matter? Urology 2016, 99: 76-83. PMID: 27667157, PMCID: PMC5191943, DOI: 10.1016/j.urology.2016.07.045.Peer-Reviewed Original ResearchConceptsProstate cancerOdds of receiving treatmentReceipt of treatmentDefinitive treatmentHispanic menWhite menD'Amico risk classificationDisease severityContext of disease severityOdds of treatmentLogistic regression analysisApproach to treatmentIntermediate-riskDecreased oddsHigh riskAA menAsian menRisk categoriesRisk classificationCancerProstateTreatmentRegression analysisMenTreatment variation
2011
The Impact of Common Genetic Variations in Genes of the Sex Hormone Metabolic Pathways on Steroid Hormone Levels and Prostate Cancer Aggressiveness
Sun T, Oh W, Jacobus S, Regan M, Pomerantz M, Freedman M, Lee G, Kantoff P. The Impact of Common Genetic Variations in Genes of the Sex Hormone Metabolic Pathways on Steroid Hormone Levels and Prostate Cancer Aggressiveness. Cancer Prevention Research 2011, 4: 2044-2050. PMID: 21900597, PMCID: PMC3773969, DOI: 10.1158/1940-6207.capr-11-0283.Peer-Reviewed Original ResearchConceptsProstate cancer aggressivenessPlasma hormone levelsCancer aggressivenessHormone levelsSingle-nucleotide polymorphismsSteroid hormone levelsAssociated with plasma levelsSex hormone-binding globulinD'Amico risk classificationLocalized prostate cancerPlasma levels of steroid hormonesSex hormone metabolic pathwayGenetic variants of genesHormone-binding globulinEstrogen metabolism pathwayInherited variationHormone metabolic pathwaysBorderline significant associationLevels of steroid hormonesAssociation of genotypesVariants of genesPlasma testosterone levelsMetabolic pathwaysTumor gradeProstate cancer
2010
Inherited Variations in AR, ESR1, and ESR2 Genes Are Not Associated With Prostate Cancer Aggressiveness or With Efficacy of Androgen Deprivation Therapy
Sun T, Lee G, Werner L, Pomerantz M, Oh W, Kantoff P, Freedman M. Inherited Variations in AR, ESR1, and ESR2 Genes Are Not Associated With Prostate Cancer Aggressiveness or With Efficacy of Androgen Deprivation Therapy. Cancer Epidemiology Biomarkers & Prevention 2010, 19: 1871-1878. PMID: 20615892, PMCID: PMC3755451, DOI: 10.1158/1055-9965.epi-10-0216.Peer-Reviewed Original ResearchConceptsAndrogen deprivation therapyResponse to ADTAssociated with prostate cancer aggressivenessProstate cancer aggressivenessDeprivation therapyESR2 geneCancer aggressivenessEfficacy of androgen deprivation therapyResponse to androgen deprivation therapySex steroid hormone receptorsAssociated with disease aggressivenessD'Amico risk classificationNormal prostate growthAggressive prostate cancerProstate cancer casesProstate cancer developmentTagging single nucleotide polymorphismsHospital-based cohortInherited variationSteroid hormone receptorsClinically relevant traitsProstate growthProstate cancerPathological stageDisease aggressiveness
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