2025
Generation of Orthogonal Gradients of the Matrix Stiffness and Chemotactic Cues in a Suspended Array of Hydrogel to Study hMSCs Migration
Xu Z, Ponek A, Thomas J, Qyang Y. Generation of Orthogonal Gradients of the Matrix Stiffness and Chemotactic Cues in a Suspended Array of Hydrogel to Study hMSCs Migration. ACS Sensors 2025, 10: 1722-1728. PMID: 40021359, DOI: 10.1021/acssensors.4c02793.Peer-Reviewed Original ResearchConceptsMatrix stiffnessChemotactic cuesHuman mesenchymal stem cellsHydrogel cylindersCell migrationDevice working principleMigration of human mesenchymal stem cellsFactor 1 alphaCellular contextOrthogonal gradientsReplica moldingGlass substratesCell migration studiesDevice fabricationWorking principleMicrofluidic devicesIn vitro assaysHydrogelsStiffnessCell typesSuspended arrayMesenchymal stem cellsConcentration gradientPoly(dimethylsiloxaneCylinder
2022
Efficient Simulation of 3D Reaction-Diffusion in Models of Neurons and Networks
McDougal RA, Conte C, Eggleston L, Newton AJH, Galijasevic H. Efficient Simulation of 3D Reaction-Diffusion in Models of Neurons and Networks. Frontiers In Neuroinformatics 2022, 16: 847108. PMID: 35655652, PMCID: PMC9152282, DOI: 10.3389/fninf.2022.847108.Peer-Reviewed Original ResearchFinite volume method simulationIrregular 3D geometryMethod simulationsDouglas-GunnDimensional simulationsHigh-dimensional simulationsWave curvatureEfficient simulationSimulationsParallel algorithmCylinderModels of neuronsNetwork modelNEURON simulatorReconstruction algorithmRegion of interestAccelerated versionConnected cylindersReaction diffusionReaction-diffusion kineticsElectrophysiological simulationsAlgorithmKinetics
2006
Optimizing Acquisition Parameters in TOF PET Scanners
Surti S, El-Fakhri G, Karp J. Optimizing Acquisition Parameters in TOF PET Scanners. 2006, 4: 2354-2359. DOI: 10.1109/nssmic.2006.354386.Peer-Reviewed Original ResearchNoise equivalent countCho SNRNon-TOF scannerScan timePET image qualityPatient dosageTime-of-flightSingles ratesOptimal acquisition parametersPET scannerTOF scannerDiameter cylinderIncreasing scan timeImage qualityReduce scan timeMeasure of signal-to-noise ratioSignal-to-noise ratioSpatial resolutionSNRAcquisition parametersLesion detectionLesionsTOFCylinderIncreased activity
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