An Approach to Intersectionally Target Mature Enteroendocrine Cells in the Small Intestine of Mice
Vossen C, Schmidt P, Wunderlich C, Mittenbühler M, Tapken C, Wienand P, Mirabella P, Cabot L, Schumacher A, Folz-Donahue K, Kukat C, Voigt I, Brüning J, Fenselau H, Wunderlich F. An Approach to Intersectionally Target Mature Enteroendocrine Cells in the Small Intestine of Mice. Cells 2024, 13: 102. PMID: 38201306, PMCID: PMC10778503, DOI: 10.3390/cells13010102.Peer-Reviewed Original ResearchConceptsEnteroendocrine cellsIntestinal epithelial cellsEEC subtypesCrypt-villus axisSmall intestineTerminal villiMouse linesTriple transgenic miceLargest endocrine organIntersectional genetic approachMature enteroendocrine cellsCre recombinase miceGastrointestinal motilityCell type-specific targetingEndocrine organHormonal secretionGastrointestinal tractGlucose metabolismMature subtypesIntestinal stem cellsFunctional readaptationTransgene expressionStop cassetteIEC typesMice
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