2000
A tetranucleotide repeat polymorphism in CYP19 and breast cancer risk
Haiman C, Hankinson S, Spiegelman D, De Vivo I, Colditz G, Willett W, Speizer F, Hunter D. A tetranucleotide repeat polymorphism in CYP19 and breast cancer risk. International Journal Of Cancer 2000, 87: 204-210. PMID: 10861475, DOI: 10.1002/1097-0215(20000715)87:2<204::aid-ijc8>3.0.co;2-3.Peer-Reviewed Original ResearchConceptsBreast cancer riskHealth Study cohortCase-control studyCancer riskHormone levelsNurses' Health Study cohortBreast cancer case-control studyElevated estrogen levelsAdvanced cancer casesCancer case-control studyRepeat polymorphismTetranucleotide repeat polymorphismConversion of androgensGreater frequencyKey steroidogenic enzymesSignificant greater frequencyDistant metastasisStudy cohortEstrogen levelsCYP19 allelesBreast cancerCancer casesAllele carriersEstrone sulfateNonsignificant increase
1993
Aromatase immunoreactivity in the rat brain: Gonadectomy-sensitive hypothalamic neurons and an unresponsive “limbic ring” of the lateral septum-bed nucleus-amygdala complex
Jakab RL, Horvath TL, Leranth C, Harada N, Naftolin F. Aromatase immunoreactivity in the rat brain: Gonadectomy-sensitive hypothalamic neurons and an unresponsive “limbic ring” of the lateral septum-bed nucleus-amygdala complex. The Journal Of Steroid Biochemistry And Molecular Biology 1993, 44: 481-498. PMID: 8476763, DOI: 10.1016/0960-0760(93)90253-s.Peer-Reviewed Original ResearchConceptsAromatase-immunoreactive neuronsRat brainAromatase systemStria terminalisLateral septal areaDorsomedial hypothalamic nucleusCentral amygdaloid nucleusMidline thalamic regionAxon-like processesDorsolateral hypothalamic areaNeuron systemConversion of androgensLaterodorsal divisionSubincertal nucleusHuman placental aromataseAromatase immunoreactivityBrain distributionGonadectomized ratsHypothalamic areaHypothalamic neuronsAmygdaloid nucleusLimbic areasHypothalamic nucleiZona incertaSeptal area
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