2018
Peptides derived from the histidine–proline rich glycoprotein bind copper ions and exhibit anti-angiogenic properties
Magrì A, Grasso G, Corti F, Finetti F, Greco V, Santoro AM, Sciuto S, La Mendola D, Morbidelli L, Rizzarelli E. Peptides derived from the histidine–proline rich glycoprotein bind copper ions and exhibit anti-angiogenic properties. Dalton Transactions 2018, 47: 9492-9503. PMID: 29963662, DOI: 10.1039/c8dt01560k.Peer-Reviewed Original ResearchConceptsElectron paramagnetic resonanceCircular dichroismSpray ionization mass spectrometryPotential drug delivery systemElectron spray ionization mass spectrometryMeans of potentiometryIonization mass spectrometryDrug delivery systemsAmidic bondCopper ionsRole of copperParamagnetic resonanceMass spectrometryComplex speciesTrehalose derivativesProdrug systemEnzymatic degradationDelivery systemCopperPeptidesPotentiometryBondsUVSpectrometryDichroism
2016
Copper incorporated microporous chitosan-polyethylene glycol hydrogels loaded with naproxen for effective drug release and anti-infection wound dressing
Mishra S, Mary D, Kannan S. Copper incorporated microporous chitosan-polyethylene glycol hydrogels loaded with naproxen for effective drug release and anti-infection wound dressing. International Journal Of Biological Macromolecules 2016, 95: 928-937. PMID: 27984151, DOI: 10.1016/j.ijbiomac.2016.10.080.Peer-Reviewed Original ResearchConceptsMoisture permeabilityEnhanced mechanical stabilityStability of filmsDrug releaseCell adhesion testsIncorporated hydrogelsMechanical propertiesEfficiency of CuMicroporous surfaceAbsorption capabilityAdhesion testHydrogel filmsMechanical stabilityChitosan filmsFilmsAntibacterial testsDegradation studiesHydrated conditionsRelease of CuWound dressingsGlycol hydrogelsEffective drug releaseHydrogelsCopper ionsCu
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