2025
α-Latrotoxin Actions in the Absence of Extracellular Ca2+ Require Release of Stored Ca2+
Blackburn J, Islam Q, Benlaouer O, Tonevitskaya S, Petitto E, Ushkaryov Y. α-Latrotoxin Actions in the Absence of Extracellular Ca2+ Require Release of Stored Ca2+. Toxins 2025, 17: 73. PMID: 39998090, PMCID: PMC11860464, DOI: 10.3390/toxins17020073.Peer-Reviewed Original ResearchConceptsAbsence of extracellular Ca<sup>2+</sup> anRelease of stored Ca2+Store-operated Ca<sup>2+</sup> entryExtracellular Ca<sup>2+</sup>Absence of extracellular Ca2Nerve terminalsCytosolic Ca<sup>2+</sup>Neurotransmitter releaseOpening of Ca<sup>2+</sup> channelsControl of neurotransmitter releaseRelease of neurotransmittersIntracellular storesExtracellular Ca2BAPTA-AMG protein-coupled receptorsMouse neuromuscular junctionCation ionophoreSensitive to inhibitorsCa2+Neuromuscular junctionNerveNeurotransmitterPhysiological controlReleaseInflux
2014
The Role of Pak-Interacting Exchange Factor-β Phosphorylation at Serines 340 and 583 by PKCγ in Dopamine Release
Shirafuji T, Ueyama T, Yoshino K, Takahashi H, Adachi N, Ago Y, Koda K, Nashida T, Hiramatsu N, Matsuda T, Toda T, Sakai N, Saito N. The Role of Pak-Interacting Exchange Factor-β Phosphorylation at Serines 340 and 583 by PKCγ in Dopamine Release. Journal Of Neuroscience 2014, 34: 9268-9280. PMID: 25009260, PMCID: PMC6608353, DOI: 10.1523/jneurosci.4278-13.2014.Peer-Reviewed Original ResearchConceptsDopamine releaseProtein kinase CRegulated exocytosisKnock-downGuanine nucleotide exchange factorAS/AGU ratNucleotide exchange factorPC12 cellsParkinsonian syndromesDopamine in vivoExchange factorControl of neurotransmitter releasePhosphoproteomic analysisNonsense mutationDopamineSer583PhosphorylationPhosphorylation levelsProtein kinase C inhibitorStriatumNeurotransmitter releaseSer340Kinase CTherapeutic targetPC12
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply