2023
Structure of the native chemotaxis core signaling unit from phage E-protein lysed E. coli cells
Cassidy C, Qin Z, Frosio T, Gosink K, Yang Z, Sansom M, Stansfeld P, Parkinson J, Zhang P. Structure of the native chemotaxis core signaling unit from phage E-protein lysed E. coli cells. MBio 2023, 14: e00793-23. PMID: 37772839, PMCID: PMC10653900, DOI: 10.1128/mbio.00793-23.Peer-Reviewed Original ResearchConceptsCore signalling unitChemosensory arraysLyse E. coli cellsCryo-electron tomographyBacterial chemotaxisSignal transductionCell movementEscherichia coli</i>.Sensing machinerySensory signal transductionSignaling unitStructural basisMolecular mechanismsMechanistic hypothesesDesign new experimentsChemotaxisCellsComplete structurePhageMotilityTransductionMachineryUbiquitous behavior
2021
Different roles of Numb-p72 and Numb-p65 on the trafficking of metabotropic glutamate receptor 5
Wang N, Wang D, Hou X, Li X, Shen Y. Different roles of Numb-p72 and Numb-p65 on the trafficking of metabotropic glutamate receptor 5. Molecular Biology Reports 2021, 48: 595-600. PMID: 33394235, DOI: 10.1007/s11033-020-06103-0.Peer-Reviewed Original ResearchConceptsClathrin-coated vesiclesIsoforms of NumbHEK293T cellsMetabotropic glutamate receptor 5Receptor 5Numb isoformsGlutamate receptor 5Expression patternsMembrane expressionExpression of metabotropic glutamate receptor 5TraffickingIsoformsBinding to mGluR5Complete structureExpressionMGluR5 trafficking
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