Gastric Carcinomas With Lymphoid Stroma
Hissong E, Ramrattan G, Zhang P, Zhou X, Young G, Klimstra D, Shia J, Fernandes H, Yantiss R. Gastric Carcinomas With Lymphoid Stroma. The American Journal Of Surgical Pathology 2018, 42: 453-462. PMID: 29438172, DOI: 10.1097/pas.0000000000001018.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkers, TumorBiopsyCarcinomaDNA Mismatch RepairFemaleGenetic Predisposition to DiseaseHerpesvirus 4, HumanHigh-Throughput Nucleotide SequencingHumansImmunohistochemistryIn Situ HybridizationLymphocytes, Tumor-InfiltratingMaleMicrosatellite InstabilityMiddle AgedMutationPhenotypeRetrospective StudiesRNA, ViralStomach NeoplasmsStromal CellsConceptsPD-L1 expressionEpstein-Barr virusLymphoid stromaGastric carcinomaPD-L1Frequent PD-L1 expressionSusceptible to checkpoint inhibitorsConventional gastric cancerTumor-infiltrating lymphocytesTumor mutational burdenEBV-encoded RNASubgroup of tumorsComprehensive Cancer PanelSpectrum of molecular changesCancer Genome Atlas studyEvaluated molecular alterationsIn situ hybridizationMismatch repair statusCheckpoint inhibitorsCancer Genome Atlas datasetHER2 amplificationInfiltrating lymphocytesGlandular differentiationKRAS alterationsTP53 variants
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