2023
Multi-omic analysis reveals metabolic pathways that characterize right-sided colon cancer liver metastasis
Morris M, Jain A, Sun B, Kurbatov V, Muca E, Zeng Z, Jin Y, Roper J, Lu J, Paty P, Johnson C, Khan S. Multi-omic analysis reveals metabolic pathways that characterize right-sided colon cancer liver metastasis. Cancer Letters 2023, 574: 216384. PMID: 37716465, PMCID: PMC10620771, DOI: 10.1016/j.canlet.2023.216384.Peer-Reviewed Original ResearchConceptsLiver metastasesColon cancer liver metastasisCancer liver metastasesSided colon cancerSubset of patientsGrowth factor betaMulti-omics analysisFatty acid oxidationMetastatic diseaseInferior survivalClinical differencesClinical behaviorUntargeted metabolomics analysisTumor behaviorColon cancerBile acidsTumor cell metabolismFactor betaPatientsMetastasisPI3K-AktReactive oxygen speciesMEK-ERKLiquid chromatography-mass spectrometryRCC
2013
Evaluation of YO-PRO-1 as an early marker of apoptosis following radiofrequency ablation of colon cancer liver metastases
Fujisawa S, Romin Y, Barlas A, Petrovic L, Turkekul M, Fan N, Xu K, Garcia A, Monette S, Klimstra D, Erinjeri J, Solomon S, Manova-Todorova K, Sofocleous C. Evaluation of YO-PRO-1 as an early marker of apoptosis following radiofrequency ablation of colon cancer liver metastases. Cytotechnology 2013, 66: 259-273. PMID: 24065619, PMCID: PMC3918265, DOI: 10.1007/s10616-013-9565-3.Peer-Reviewed Original ResearchColorectal-cancer liver metastasesYO-PRO-1Liver metastasesColon cancer liver metastasisLiver tissuePropidium iodineCancer liver metastasesMouse liverMarkers of cell deathMinimally invasive treatmentMouse liver parenchymaSurrounding liver tissueMarkers of apoptosisSurgical resectionPlasma membrane injuryRadiofrequency ablationDynamic CTPI signalingNonsurgical patientsPathological examinationTarget tumorsInvasive treatmentPositive cellsBiopsy samplesNormal mouse liver
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