2006
Performance monitoring and stop signal inhibition in abstinent patients with cocaine dependence
Li CS, Milivojevic V, Kemp K, Hong K, Sinha R. Performance monitoring and stop signal inhibition in abstinent patients with cocaine dependence. Drug And Alcohol Dependence 2006, 85: 205-212. PMID: 16725282, DOI: 10.1016/j.drugalcdep.2006.04.008.Peer-Reviewed Original ResearchConceptsImpaired response inhibitionStop-signal taskResponse inhibitionCognitive processesCocaine-dependent patientsSignal taskResponse readinessTask-related cognitive processesCritical cognitive mechanismsPerformance monitoringMeasures of impulsivityEducation-matched healthy controlsSignal reaction timeAbstinent cocaine-dependent patientsHorse-race modelCognitive mechanismsPSS effectCocaine subjectsRace modelHealthy controlsSubstance abusersAbstinent patientsSSRTStop signalCocaine dependence
2004
Perfusion abnormalities and decision making in cocaine dependence
Tucker KA, Potenza MN, Beauvais JE, Browndyke JN, Gottschalk PC, Kosten TR. Perfusion abnormalities and decision making in cocaine dependence. Biological Psychiatry 2004, 56: 527-530. PMID: 15450790, DOI: 10.1016/j.biopsych.2004.06.031.Peer-Reviewed Original ResearchConceptsIowa Gambling TaskFrontal gyrusCocaine-dependent patientsPoor decision-making abilitiesBetter IGT performanceCard selectionAbstinent cocaine-dependent patientsMiddle frontal gyrusMedial frontal gyrusSuperior frontal gyrusDecision-making abilityAnterior cingulate gyrusCognitive factorsGambling TaskResponse inhibitionCognitive functioningIGT performanceImpaired performanceIGT scoresSeverity of impairmentCingulate gyrusBrain regionsGyrusCocaine dependenceCocaine abusers
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