2024
Correlation Between Pain, Disease Activity, and Rheumatoid Factor Positivity in Patients with Chikungunya Arthritis
Amaral J, Schoen R, Bingham C, Firmino P, Cândido E. Correlation Between Pain, Disease Activity, and Rheumatoid Factor Positivity in Patients with Chikungunya Arthritis. The Yale Journal Of Biology And Medicine 2024, 97: 417-422. PMID: 39703605, PMCID: PMC11650909, DOI: 10.59249/hgxw4816.Peer-Reviewed Original ResearchConceptsVisual analog scaleChikungunya arthritisDisease activityDAS28-ESRRheumatoid factorPain visual analog scaleChikungunya feverDisease Activity ScoreRheumatoid factor positivityDisease activity indexChikungunya virusSignificantly with disease activityAcute viral diseasePain intensityAnalog scaleRetrospective cohortPain riskProspective cohortFactor positivityImproved therapiesActivity scoreClinical evaluationJoint symptomsPainAcute phase
2022
From COVID to fibrosis: lessons from single-cell analyses of the human lung
Justet A, Zhao AY, Kaminski N. From COVID to fibrosis: lessons from single-cell analyses of the human lung. Human Genomics 2022, 16: 20. PMID: 35698166, PMCID: PMC9189802, DOI: 10.1186/s40246-022-00393-0.Peer-Reviewed Original ResearchConceptsSingle-cell RNA-sequencing technologySingle-cell RNA sequencingRNA-sequencing technologyGene expression patternsMonocyte-derived macrophage populationSingle-cell analysisCell populationsLung diseaseCellular phenotypesRNA sequencingExpression patternsGene expressionAberrant repairMultiple tissuesPulmonary fibrosisMechanisms of diseaseFibrotic interstitial lung diseaseLife-threatening complicationsProgressive lung diseaseCOVID-19 pneumoniaInterstitial lung diseaseParenchymal lung diseaseAcute viral diseaseMacrophage populationsNovel cell
2021
COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms
Malone R, Tisdall P, Fremont-Smith P, Liu Y, Huang X, White K, Miorin L, Moreno E, Alon A, Delaforge E, Hennecker C, Wang G, Pottel J, Blair R, Roy C, Smith N, Hall J, Tomera K, Shapiro G, Mittermaier A, Kruse A, García-Sastre A, Roth B, Glasspool-Malone J, Ricke D. COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms. Frontiers In Pharmacology 2021, 12: 633680. PMID: 33833683, PMCID: PMC8021898, DOI: 10.3389/fphar.2021.633680.Peer-Reviewed Original ResearchSARS-CoV-2 infectionCOVID-19 diseaseSARS-CoV-2Mast cell activationClinical COVID-19Acute viral diseaseMechanism of actionSymptoms of COVID-19Dose selectionClinical dataTreatment strategiesTreatment of COVID-19 diseaseHistamine releaseCell activationWell-characterized drugsCOVID-19 symptomsClinical COVID-19 diseaseOral formFamotidineMedical countermeasuresDiseaseInpatient treatmentCOVID-19InfectionSymptoms
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