1998
High-dose chemotherapy: how resistant is breast cancer?
Pusztai L, Hortobagyi G. High-dose chemotherapy: how resistant is breast cancer? Drug Resistance Updates 1998, 1: 62-72. PMID: 17092798, DOI: 10.1016/s1368-7646(98)80216-1.Peer-Reviewed Original ResearchHigh-dose chemotherapyClinical drug resistanceBreast cancerDrug resistancePartial responseClinical patternResponse rateComplete response rateHigh-dose therapyInitial complete responseObjective response rateStandard-dose chemotherapyDifferent clinical patternsMajority of patientsPrimary drug resistanceStem cell supportHigh cure ratesDrug-resistant clonesInduction therapyInitial chemosensitivityPathologic resistanceStable diseaseCancer dieOverall survivalComplete response
1982
Flow cytometric analysis of DNA content of bone marrow cells in patients with plasma cell myeloma: clinical implications.
Bunn P, Krasnow S, Makuch R, Schlam M, Schechter G. Flow cytometric analysis of DNA content of bone marrow cells in patients with plasma cell myeloma: clinical implications. Blood 1982, 59: 528-35. PMID: 6800416, DOI: 10.1182/blood.v59.3.528.bloodjournal593528.Peer-Reviewed Original ResearchConceptsTumor DNA contentMyeloma patientsPlasma cell myelomaAneuploid tumor cellsPlasma cellsWaldenstrom's macroglobulinemiaCell myelomaTumor cellsTime of diagnosisTime of relapseIndependent prognostic significanceCourse of illnessClinical drug resistancePotential clinical usefulnessBone marrow cellsDNA contentClinical relapseRenal failureSerum creatininePrognostic significanceDiploid tumorsAneuploid tumorsDevelopment of aneuploidyClinical significanceClinical usefulnessFlow Cytometric Analysis of DNA Content of Bone Marrow Cells in Patients With Plasma Cell Myeloma: Clinical Implications
Bunn P, Krasnow S, Makuch R, Schlam M, Schechter G. Flow Cytometric Analysis of DNA Content of Bone Marrow Cells in Patients With Plasma Cell Myeloma: Clinical Implications. Blood 1982, 59: 528-535. DOI: 10.1182/blood.v59.3.528.528.Peer-Reviewed Original ResearchTumor DNA contentMyeloma patientsPlasma cell myelomaAneuploid tumor cellsPlasma cellsWaldenstrom's macroglobulinemiaCell myelomaTumor cellsIndependent prognostic significanceTime of diagnosisTime of relapseCourse of illnessClinical drug resistancePotential clinical usefulnessBone marrow cellsFlow cytometric analysisDNA contentClinical relapseRenal failureSerum creatininePrognostic significanceDiploid tumorsAneuploid tumorsDevelopment of aneuploidyClinical significance
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