Gut microbiome in association with chemotherapy‐induced toxicities among patients with breast cancer
Nguyen S, Tran H, Long J, Shrubsole M, Cai H, Yang Y, Cai Q, Tran T, Zheng W, Shu X. Gut microbiome in association with chemotherapy‐induced toxicities among patients with breast cancer. Cancer 2024, 130: 2014-2030. PMID: 38319284, DOI: 10.1002/cncr.35229.Peer-Reviewed Original ResearchGut microbiomeChemotherapy-induced toxicityRisk of severe neutropeniaReductive tricarboxylic acid cycleMetabolic pathwaysGut microbial diversityTricarboxylic acid cycleSevere nausea/vomitingSevere neutropeniaBreast cancerFamily LachnospiraceaeIncreased risk of severe neutropeniaShotgun metagenomicsClass NegativicutesGut microbiotaB-diversityMicrobial diversityAcid cycleChao1 indexSevere hematologic toxicityA-diversityFirst-line treatmentMicrobiomeMultivariate logistic regressionGut
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