Early-onset appendiceal adenocarcinoma (EOAA): 10-year experience from a single center.
Gujarathi R, Belmont E, Rodman C, Bansal V, Setia N, Alpert L, Hart J, Moller M, Eng O, Lee G, Chin J, Amin M, Polite B, Liao C, Turaga K, Shergill A. Early-onset appendiceal adenocarcinoma (EOAA): 10-year experience from a single center. Journal Of Clinical Oncology 2024, 42: 4178-4178. DOI: 10.1200/jco.2024.42.16_suppl.4178.Peer-Reviewed Original ResearchOutcomes of overall survivalAppendiceal adenocarcinomaEarly-onset diseasePerineural invasionCytoreductive surgeryUnivariate Cox proportional hazards regression analysisCox proportional hazards regression analysisIncidence of early-onsetAssociated with poor outcomesGrade 3 diseaseProportional hazards regression analysisTargetable genomic alterationsHigh-volume centersLymph node metastasisRecords of patientsHazards regression analysisGermline mutation testingLate-onset diseaseCHEK2 mutationsMedian OSVulnerable patient populationCancer ptsOverall survivalLocalized diseaseMetastatic/recurrent disease
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