2012
2. Screening for clinical correlation with 14 cerebral RNA editing sites in temporal lobe epilepsy
Krestel H, Nirkko A, von Lehe M, Jagella C, Moskau-Hartmann S, Becker A, Elger C, Seeburg P. 2. Screening for clinical correlation with 14 cerebral RNA editing sites in temporal lobe epilepsy. Clinical Neurophysiology 2012, 123: e108. DOI: 10.1016/j.clinph.2012.03.066.Peer-Reviewed Original ResearchTemporal lobe epilepsyNon-epileptic subjectsMesial temporal lobe epilepsyLobe epilepsyTLE patientsEpilepsy durationEpilepsy severityCerebral RNANon-significant decreaseIon channelsMTLE patientsPotassium channel Kv1.1Seizure frequencyCerebral excitabilityEpilepsy onsetClinical correlationClinical markersInterictal EEGReceptor BPatientsStrong inverse correlationElectrophysiological propertiesBrain tissueEpilepsyChannel Kv1.1
2002
Magnetic Resonance Spectroscopic Studies of Neurotransmitters and Energy Metabolism in Epilepsy
Petroff O, Pan J, Rothman D. Magnetic Resonance Spectroscopic Studies of Neurotransmitters and Energy Metabolism in Epilepsy. Epilepsia 2002, 43: 40-50. DOI: 10.1046/j.1528-1157.2002.043s1040.x.Peer-Reviewed Original ResearchCerebral electrical activityGlutamate-glutamine cycleGABA synthesisGABA levelsRefractory complex partial seizuresOccipital GABA levelsLower GABA levelsCerebral energy stateComplex partial seizuresElectrical activityKetone body metabolismΓ-aminobutyric acid (GABA) metabolismHuman visual cortexCerebral excitabilityGlutamate reuptakePartial seizuresRefractory epilepsyGABAergic neuronsKetogenic dietBrain metabolismCortical excitabilitySynaptic glutamateBrain glutamateMyoclonic epilepsyNeurotransmitter pool
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