2008
Regulation of IKKβ by miR-199a affects NF-κB activity in ovarian cancer cells
Chen R, Alvero AB, Silasi DA, Kelly MG, Fest S, Visintin I, Leiser A, Schwartz PE, Rutherford T, Mor G. Regulation of IKKβ by miR-199a affects NF-κB activity in ovarian cancer cells. Oncogene 2008, 27: 4712-4723. PMID: 18408758, PMCID: PMC3041589, DOI: 10.1038/onc.2008.112.Peer-Reviewed Original ResearchConceptsOvarian cancer cellsEOC cellsTumor samplesNuclear factor-κB activationCancer cellsOvarian cancer ascitesChemoresistant ovarian cancerNF-κB pathwayNF-κB activityPatient tumor samplesIKKβ pathwayTLR-MyD88Chronic inflammationEffective therapyCancer ascitesOvarian cancerInflammatory microenvironmentIKKβ expressionSolid tumorsTumor progressionCancer progressionIκB kinaseAbnormal formsMicroRNA hsaTissue repair
1990
Association of cocaine use with sperm concentration, motility, and morphology
Bracken M, Eskenazi B, Sachse K, McSharry J, Hellenbrand K, Leo-Summers L. Association of cocaine use with sperm concentration, motility, and morphology. Fertility And Sterility 1990, 53: 315-322. PMID: 2298313, DOI: 10.1016/s0015-0282(16)53288-9.Peer-Reviewed Original ResearchConceptsCocaine useRisk factorsMale subfertilityMajor risk factorGeneral male populationFirst semen analysisUse of cocaineHigh prevalenceLow sperm motilitySperm countDiagnostic InterviewMale populationSemen analysisHistory of useSperm concentrationAbnormal formsSubfertilityMore yearsSperm motilityCocaineMenAssociationLarge proportionMotilityYears
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