2024
BCMA CAR-T induces complete and durable remission in plasmablastic lymphoma synchronous transformation of chronic lymphocytic leukemia: Case report and literature review
Feng S, Xiong Y, Liu W, Liu H, Sui W, Zheng P, Sun M, Hu K, Zhang Y. BCMA CAR-T induces complete and durable remission in plasmablastic lymphoma synchronous transformation of chronic lymphocytic leukemia: Case report and literature review. Critical Reviews In Oncology/Hematology 2024, 205: 104551. PMID: 39510436, DOI: 10.1016/j.critrevonc.2024.104551.Peer-Reviewed Original ResearchConceptsChronic lymphocytic leukemiaPlasmablastic lymphomaCAR-TLymphocytic leukemiaTransformation of chronic lymphocytic leukemiaCAR-T cell treatmentBruton tyrosine kinase inhibitorPatient's chronic lymphocytic leukemiaRight supraclavicular massNovel targeted agentsTyrosine kinase inhibitorsRichter transformationSupraclavicular massBrentuximab vedotinTargeted therapyTargeted agentsRare caseBone marrowCase reportTherapy choiceKinase inhibitorsInnovative therapiesCell treatmentTherapyBCMA
2020
Stem Cell Therapy to Improve Acute Myocardial Infarction Remodeling
Gorecka J, Dardik A. Stem Cell Therapy to Improve Acute Myocardial Infarction Remodeling. 2020, 299-329. DOI: 10.1007/978-3-030-56954-9_14.ChaptersHeart failureMyocardial infarctionClinical trialsEjection fractionCellular sourceCell therapyEnd-stage pathologyCause of deathStem cell efficacyStem cell treatmentStem cell therapyMI injuryVentricular dilationModest efficacyMyocardial recoveryHeart diseaseRemodeling changesSurgical careIschemic environmentAdult myocardiumDelivery methodsCell efficacyCell treatmentLack of standardizationTrials
2016
BPX-501 Cells (Donor T Cells Transduced with iC9 Suicide Gene) Treatment Following TCR Alpha Beta Depleted Stem Cell Transplantation in Adults and Children with Hematological Disorders
Vusirikala M, Naik S, Maziarz R, Baumeister S, Aquino V, Ma H, Moseley A, Woolfrey A, Krishnamurti L, Chen G, Sandmaier B, Bertaina A, Perales M, Williams D, Kapoor N. BPX-501 Cells (Donor T Cells Transduced with iC9 Suicide Gene) Treatment Following TCR Alpha Beta Depleted Stem Cell Transplantation in Adults and Children with Hematological Disorders. Transplantation And Cellular Therapy 2016, 22: s361. DOI: 10.1016/j.bbmt.2015.11.863.Peer-Reviewed Original Research
2014
Integrin-driven monocyte to dendritic cell conversion in modified extracorporeal photochemotherapy
Gonzalez AL, Berger CL, Remington J, Girardi M, Tigelaar RE, Edelson RL. Integrin-driven monocyte to dendritic cell conversion in modified extracorporeal photochemotherapy. Clinical & Experimental Immunology 2014, 175: 449-457. PMID: 24188174, PMCID: PMC3927905, DOI: 10.1111/cei.12231.Peer-Reviewed Original ResearchConceptsCutaneous T-cell lymphomaDC differentiationHuman leucocyte antigen DDendritic antigen-presenting cellsPlasma proteinsAntigen-presenting cellsT-cell lymphomaECP efficacyHost diseaseClinical efficacySafety profileSelective immunizationCell lymphomaAntigen DCell treatmentMonocytesPhenotypic expressionEfficacyNovel mechanismECPDifferentiationCD83ImmunosuppressionCD86Fibronectin
2010
To B or not to B—pathogenic and regulatory B cells in autoimmune diabetes
Wong F, Hu C, Xiang Y, Wen L. To B or not to B—pathogenic and regulatory B cells in autoimmune diabetes. Current Opinion In Immunology 2010, 22: 723-731. PMID: 21050736, DOI: 10.1016/j.coi.2010.10.002.Peer-Reviewed Original Research
1995
Ca2+/calmodulin-dependent protein kinase II activation and regulation of adrenal glomerulosa Ca2+ signaling
Fern RJ, Hahm MS, Lu HK, Liu LP, Gorelick FS, Barrett PQ. Ca2+/calmodulin-dependent protein kinase II activation and regulation of adrenal glomerulosa Ca2+ signaling. American Journal Of Physiology 1995, 269: f751-f760. PMID: 8594869, DOI: 10.1152/ajprenal.1995.269.6.f751.Peer-Reviewed Original ResearchConceptsCaMKII activityBovine adrenal glomerulosa cellsDepolarization-induced increaseAdrenal glomerulosa cellsDepolarization-induced Ca2Voltage-gated Ca2Independent CaMKII activityElevated extracellular potassiumDependent protein kinase II (CaMKII) activationCaMKII inhibitor peptideAgonist-induced stimulationAldosterone secretagoguesAngiotensin IIGlomerulosa cellsKinase activityExtracellular potassiumImportance of CaMKIIIntracellular Ca2Dependent protein kinase IIProtein kinase IICell treatmentKN-62Calmodulin antagonistsCell-permeable inhibitorChannel activity
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