2017
Histones and Neutrophil Extracellular Traps Enhance Tubular Necrosis and Remote Organ Injury in Ischemic AKI
Nakazawa D, Kumar SV, Marschner J, Desai J, Holderied A, Rath L, Kraft F, Lei Y, Fukasawa Y, Moeckel GW, Angelotti ML, Liapis H, Anders HJ. Histones and Neutrophil Extracellular Traps Enhance Tubular Necrosis and Remote Organ Injury in Ischemic AKI. Journal Of The American Society Of Nephrology 2017, 28: 1753-1768. PMID: 28073931, PMCID: PMC5461800, DOI: 10.1681/asn.2016080925.Peer-Reviewed Original ResearchConceptsNeutrophil extracellular trap formationExtracellular trap formationNeutrophil extracellular trapsTubular necrosisExtracellular trapsCell necrosisTubular epithelial cell deathTubular epithelial cell necrosisRemote organ dysfunctionRemote organ injuryRemote organ damageRenal ischemic injuryTubular cell necrosisIschemia-reperfusion injuryRemote tissue injuryAdditive protective effectEpithelial cell necrosisTUNEL-positive cellsEpithelial cell deathNovel molecular targetsTrap formationIschemic AKISevere AKIKidney injuryMultiorgan dysfunction
2015
The Role of p204 in Kidney Injury
Marlier A, Huen S, Lengyel P, Cantley L. The Role of p204 in Kidney Injury. The FASEB Journal 2015, 29 DOI: 10.1096/fasebj.29.1_supplement.807.1.Peer-Reviewed Original ResearchAcute kidney injuryIschemia-reperfusion injuryRenal ischemia-reperfusion injuryChronic kidney diseaseKidney injuryPeak serum creatinine levelClassical inflammatory stimuliSerum creatinine levelsTubular cell necrosisCD45-positive cellsWhole-body knockoutAKI biomarkersCreatinine levelsKidney diseaseCHI3L1 expressionKidney ischemiaKidney fibrosisInflammasome activationInflammatory stimuliReparative phasePositive cellsTherapeutic targetBone marrowWT controlsCell necrosis
1984
Pardaxin increases solute permeability of gills and rectal gland in the dogfish shark (Squalus acanthias)
Primor N, Zadunaisky J, Murdaugh H, Boyer J, Forrest J. Pardaxin increases solute permeability of gills and rectal gland in the dogfish shark (Squalus acanthias). Comparative Biochemistry And Physiology Part C Toxicology & Pharmacology 1984, 78: 483-490. PMID: 6149101, DOI: 10.1016/0742-8413(84)90119-1.Peer-Reviewed Original Research
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