1574-P: Catecholamine-Induced Adipose Lipolysis Drives Hepatic Steatosis in Pnpla3I148M Knockin Mice
PRAKASH GOLLA J, SUH R, PAOLELLA L, STROBER J, ZHANG F, PHILBRICK W, VATNER D. 1574-P: Catecholamine-Induced Adipose Lipolysis Drives Hepatic Steatosis in Pnpla3I148M Knockin Mice. Diabetes 2024, 73 DOI: 10.2337/db24-1574-p.Peer-Reviewed Original ResearchWhite adipose tissueM miceDecreased hepatic triglycerideHepatic steatosisMutant miceCatecholamine responseGonadal white adipose tissueBeta-adrenergic blockadeHepatic triglycerideWhite adipose tissue functionResponse to CLHigh-sucrose dietHepatic triglyceride contentWT miceM mutationExtrahepatic sourcesAdrenergic blockadeHepatic triglyceride biosynthesisAgonist CLEx vivoInsulin responseI148MMiceFatty liverAdipose tissue
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