Peptide-Nanoparticle Hybrid SERS Probe for Dynamic Detection of Active Cancer Biomarker Enzymes
Liu GL, Chen FF, Ellman JA, Lee LP. Peptide-Nanoparticle Hybrid SERS Probe for Dynamic Detection of Active Cancer Biomarker Enzymes. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2006, 2006: 795-798. PMID: 17946000, DOI: 10.1109/iembs.2006.260259.Peer-Reviewed Original ResearchConceptsRaman signalEarly-stage cancer screeningCancer-related proteasesIntrinsic Raman signalsHigh reaction specificityEarly cancer diagnosisRaman spectral signalsSERS probeSerine protease presentProstate cancer markerSensitive detectionCancer cell identificationOptical probeSitu detectionNanocrescentsCancer markersReaction volumeHigh specificityTAG moleculesPSA concentrationDynamic detectionPSA proteinRadioactive probesProtease enzymeNanoprobe
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