2005
Somatic mutations of the ERBB4 kinase domain in human cancers
Soung Y, Lee J, Kim S, Wang Y, Jo K, Moon S, Park W, Nam S, Lee J, Yoo N, Lee S. Somatic mutations of the ERBB4 kinase domain in human cancers. International Journal Of Cancer 2005, 118: 1426-1429. PMID: 16187281, DOI: 10.1002/ijc.21507.Peer-Reviewed Original ResearchConceptsErbB4 kinase domainsKinase domainSomatic mutationsERBB4 mutationsHuman cancersPolymerase chain reaction-single-strand conformation polymorphism assayDevelopment of human cancersK-rasGastric carcinomaNonsmall cell lung cancerMissense mutationsK-ras gene mutationMutations of EGFRCell lung cancerMutation analysisSignaling pathwayDuplication mutationsMutationsEGFR familyERBB2 genePolymorphism assayBreast carcinomaGene mutationsBRAF geneErbB4
2004
PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas
Lee J, Soung Y, Kim S, Lee H, Park W, Nam S, Kim S, Lee J, Yoo N, Lee S. PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene 2004, 24: 1477-1480. PMID: 15608678, DOI: 10.1038/sj.onc.1208304.Peer-Reviewed Original ResearchConceptsNon-small-cell lung cancerPIK3CA mutationsBreast carcinomaHepatocellular carcinomaPIK3CA geneGastric carcinomaHuman cancersAcute leukemiaPolymerase chain reaction-single-strand conformation polymorphism assayLung cancerEarly lesionsBreast cancer carcinomasPIK3CA gene mutationsPIK3CA somatic mutationsDevelopment of human cancersPhosphoinositide-3-kinaseMutation searchMutation analysisKinase pathwayGene mutationsCarcinomaColon cancerPIK3CASomatic mutationsPolymorphism assay
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