A FISH assay efficiently screens for BRAF gene rearrangements in pancreatic acinar-type neoplasms
Wang L, Basturk O, Wang J, Benayed R, Middha S, Zehir A, Linkov I, Rao M, Aryeequaye R, Cao L, Chmielecki J, Ross J, Stephens P, Adsay V, Askan G, Balci S, Klimstra D. A FISH assay efficiently screens for BRAF gene rearrangements in pancreatic acinar-type neoplasms. Modern Pathology 2017, 31: 132-140. PMID: 28884748, DOI: 10.1038/modpathol.2017.106.Peer-Reviewed Original ResearchConceptsNext-generation sequencing studiesSequencing studiesNext-generation sequencing-based technologiesFusion partnerNext-generation sequencing-based platformsInhibited MAPK pathway activationFISH assaySequencing-based platformsSequencing-based studiesSequencing-based technologiesNext-generation sequencing-based analysisSequencing-based analysisGene rearrangementsBRAF gene rearrangementsNext-generation sequencingFrequent fusion partnerBRAF fusionsMAPK pathway activationAcinar cell carcinomaBRAF gene fusionsGene fusionsFISH analysisPotential therapeutic targetFISH investigationsCell carcinoma
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