2019
Transcriptome-wide piRNA profiling in human brains for aging genetic factors.
Mao Q, Fan L, Wang X, Lin X, Cao Y, Zheng C, Zhang Y, Zhang H, Garcia-Milian R, Kang L, Shi J, Yu T, Wang K, Zuo L, Li CR, Guo X, Luo X. Transcriptome-wide piRNA profiling in human brains for aging genetic factors. 2019, 4 PMID: 32149191, PMCID: PMC7059831.Peer-Reviewed Original ResearchPIWI-interacting RNAsTransposable elementsAge-associated genesCritical genetic determinantsGenomic integrityExpression regulationCancer stem cellsMicroarray technologyGenetic determinantsStem cellsExpression levelsRenewal capacityMolecular featuresBiological systemsPotential roleGenetic factorsYears of survivalUnderlying mechanismHuman prefrontal cortexGermlineGenesRNADisease statusMultiple testingPrefrontal cortex
2017
Conditional Survival Analysis of Patients With Locally Advanced Laryngeal Cancer: Construction of a Dynamic Risk Model and Clinical Nomogram
Sheu T, Vock D, Mohamed A, Gross N, Mulcahy C, Zafereo M, Gunn G, Garden A, Sevak P, Phan J, Lewin J, Frank S, Beadle B, Morrison W, Lai S, Hutcheson K, Marai G, Canahuate G, Kies M, El-Naggar A, Weber R, Rosenthal D, Fuller C. Conditional Survival Analysis of Patients With Locally Advanced Laryngeal Cancer: Construction of a Dynamic Risk Model and Clinical Nomogram. Scientific Reports 2017, 7: 43928. PMID: 28276466, PMCID: PMC5343446, DOI: 10.1038/srep43928.Peer-Reviewed Original ResearchConceptsConditional overall survivalRecurrence free survivalLocally advanced laryngeal cancerOverall survivalAdvanced laryngeal cancerYears of survivalConditional survivalLaryngeal cancerYear actuarial overall survivalActuarial overall survivalTreatment-related toxicityAssociated with recurrenceSurvival analysis of patientsAnalysis of patientsFollow-up timeRecords of patientsConditional survival analysisNodal diseaseFree survivalPrognostic factorsNodal groupsPredictive nomogramClinical nomogramHigher mortality riskPatient cohort
2002
Liposomal Doxorubicin for Treatment of Metastatic Chemorefractory Vulvar Adenocarcinoma
Huang GS, Juretzka M, Ciaravino G, Kohler S, Teng NN. Liposomal Doxorubicin for Treatment of Metastatic Chemorefractory Vulvar Adenocarcinoma. Gynecologic Oncology 2002, 87: 313-318. PMID: 12468332, DOI: 10.1006/gyno.2002.6830.Peer-Reviewed Original ResearchConceptsVulvar adenocarcinomaLiposomal doxorubicinPelvic lymph node dissectionGroin lymph nodesLymph node dissectionExtramammary Paget's diseaseYears of survivalWarrants further investigationBulky involvementGroin irradiationInitial therapyNode dissectionMultiagent chemotherapyRadical vulvectomyGynecologic malignanciesMetastatic diseaseLymph nodesInitial diagnosisMetastatic lesionsPaget's diseaseDramatic regressionRare entityDoxil treatmentEffective treatmentSubcutaneous lesions
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