2025
Combining Ketamine Infusions and Written Exposure Therapy for Chronic PTSD: An Open-Label Trial.
Feder A, Brown O, Rutter S, Cahn L, Overbey J, Seeley S, Yu A, Bonanno P, Fremont R, Delgado A, Jha M, Costi S, Yehuda R, Schiller D, Pietrzak R, Charney D, Sloan D, Murrough J. Combining Ketamine Infusions and Written Exposure Therapy for Chronic PTSD: An Open-Label Trial. The Journal Of Clinical Psychiatry 2025, 86 PMID: 40215385, DOI: 10.4088/jcp.24m15622.Peer-Reviewed Original ResearchConceptsChronic posttraumatic stress disorderPosttraumatic stress disorderKetamine infusionPosttraumatic stress disorder symptom severityClinician-Administered PTSD ScalePosttraumatic stress disorder symptomsDSM-5</i>Written Exposure TherapyOpen-label clinical trialIntravenous ketamine infusionSevere symptom levelsPTSD ScaleCAPS-5Exposure therapyStress disorderOpen-label trialSymptom levelsSymptom severityTreatment respondersPreliminary efficacyClinical trialsPreliminary findingsCombined treatmentLarge-scale randomized controlled trialsRandomized Controlled Trials
2024
Written exposure therapy for veterans with co-occurring substance use disorders and PTSD: Study design of a randomized clinical trial
Meshberg-Cohen S, Cook J, Bin-Mahfouz A, Petrakis I. Written exposure therapy for veterans with co-occurring substance use disorders and PTSD: Study design of a randomized clinical trial. Contemporary Clinical Trials 2024, 139: 107475. PMID: 38365173, DOI: 10.1016/j.cct.2024.107475.Peer-Reviewed Original ResearchWritten Exposure TherapyPosttraumatic stress disorderEvidence-based psychotherapiesSubstance use disordersExposure therapyReduce symptoms of posttraumatic stress disorderSymptoms of posttraumatic stress disorderPTSD specialty clinicRates of posttraumatic stress disorderCo-occurring substance use disordersComorbid posttraumatic stress disorderSubstance use disorder outcomesDays of substance useTreatment-seeking veteransSubstance use disorder treatmentStress disorderAddiction outcomesTherapist involvementAddiction programsSUD treatmentSubstance useTrauma treatmentRandomized clinical trialsWriting conditionsHomework assignments
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