2023
Effectiveness of recombinant human FSH: recombinant human LH combination treatment versus recombinant human FSH alone for assisted reproductive technology in women aged 35–40 years
Bielfeld A, Schwarze J, Verpillat P, Lispi M, Fischer R, Hayward B, Chuderland D, D'Hooghe T, Krussel J. Effectiveness of recombinant human FSH: recombinant human LH combination treatment versus recombinant human FSH alone for assisted reproductive technology in women aged 35–40 years. Reproductive BioMedicine Online 2023, 48: 103725. PMID: 38593745, DOI: 10.1016/j.rbmo.2023.103725.Peer-Reviewed Original ResearchAdvanced maternal ageWomen of advanced maternal ageR-hLHR-hFSHRecombinant human FSHLive birthsClinical pregnancyOvarian stimulationHuman FSHPost hoc analysis of womenRecombinant human LHLive birth rateNormal ovarian reserveNon-interventional studyAssisted Reproductive TechnologyAnalysis of womenPost Hoc AnalysisOvarian reserveMaternal ageEffects of treatmentHuman LHAlone groupPatient groupClinical trialsART treatmentO-205 Poor mitochondrial metabolism impairs meiosis and contributes to reduced oocyte maturation rates in patients with advanced maternal age
Pietroforte S, Martins M, Ibañez E, Popovic M, Sanchez T, Vassena R, Sakkas D, Zambelli F. O-205 Poor mitochondrial metabolism impairs meiosis and contributes to reduced oocyte maturation rates in patients with advanced maternal age. Human Reproduction 2023, 38 DOI: 10.1093/humrep/dead093.251.Peer-Reviewed Original ResearchAdvanced maternal ageWomen of advanced maternal ageGerminal vesicleOocyte metabolismGV oocytesMaternal ageMeiotic maturationMaturation rateAdvanced maternal age patientsDecline of oocyte qualityFluorescence mean intensityOocyte maturation rateExtruded polar bodiesMitochondrial activityMitochondrial metabolismAneuploidy rateGV stageChi-square testHuman oocytesLoss of function studiesOocyte qualityOocyte selectionNon-invasive toolWider implicationsComprehensive metabolism
2022
Live Birth With or Without Preimplantation Genetic Testing for Aneuploidy
Yan J, Qin Y, Zhao H, Sun Y, Gong F, Li R, Sun X, Ling X, Li H, Hao C, Tan J, Yang J, Zhu Y, Liu F, Chen D, Wei D, Lu J, Ni T, Zhou W, Wu K, Gao Y, Shi Y, Lu Y, Zhang T, Wu W, Ma X, Ma H, Fu J, Zhang J, Meng Q, Zhang H, Legro R, Chen Z. Live Birth With or Without Preimplantation Genetic Testing for Aneuploidy. Obstetrical & Gynecological Survey 2022, 77: 159-161. DOI: 10.1097/01.ogx.0000822436.67205.20.Peer-Reviewed Original ResearchPreimplantation genetic testingLive birth rateIn vitro fertilizationPGT-AGenetic testingWomen of advanced maternal ageIncreased live birth rateAdvanced maternal ageBirth experienceHigh quality embryosBirth rateMaternal ageQuality embryosLive birthsMorphology scorePreimplantationAneuploidyGenetic statusWomenPrognosisScoresBirth
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