2020
An Application of the Cure Model to a Cardiovascular Clinical Trial
Sevilimedu V, Ma S, Hartigan P, Kyriakides T. An Application of the Cure Model to a Cardiovascular Clinical Trial. Statistics In Biosciences 2020, 13: 402-430. DOI: 10.1007/s12561-020-09297-w.Peer-Reviewed Original ResearchMyocardial infarctionACS eventAggressive Drug Evaluation (COURAGE) trialClinical Outcomes Utilizing RevascularizationHazard of MICardiovascular clinical trialsDrug evaluation trialsCoronary syndromeClinical trialsMedical conditionsClinical practiceSurvival analysisCure modelNovel findingsRiskTrialsCured fractionEvaluation trialsRevascularizationInfarctionSyndrome
2013
Gastroprotection in Low-Dose Aspirin Users for Primary and Secondary Prevention of ACS: Results of a Cost-Effectiveness Analysis Including Compliance
de Groot NL, van Haalen HG, Spiegel BM, Laine L, Lanas A, Focks JJ, Siersema PD, van Oijen MG. Gastroprotection in Low-Dose Aspirin Users for Primary and Secondary Prevention of ACS: Results of a Cost-Effectiveness Analysis Including Compliance. Cardiovascular Drugs And Therapy 2013, 27: 341-357. PMID: 23417566, DOI: 10.1007/s10557-013-6448-y.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAspirinCost-Benefit AnalysisDrug Therapy, CombinationGastrointestinal HemorrhageHealth Care CostsHumansMaleMiddle AgedModels, TheoreticalPatient CompliancePlatelet Aggregation InhibitorsPrimary PreventionProton Pump InhibitorsQuality-Adjusted Life YearsSecondary PreventionConceptsAcute coronary syndromeProton pump inhibitorsUpper GI bleedingSecondary preventionGI bleedingASA monotherapyPPI complianceElevated riskLow-dose ASA usersLow-dose aspirin usersUpper GI side effectsGI side effectsUpper gastrointestinal complicationsCombination of ASABase-case patientProbabilistic sensitivity analysesCost-effectiveness analysisASA usersGastrointestinal complicationsGastroprotective strategiesAspirin usersCoronary syndromePPI useACS eventCase patients
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