2025
Critical genomic insights into vancomycin-resistant Enterococcus faecium in Lebanon
Osman M, Yassine I, Hassan J, Ericson J, Schiff S, Tajani A, Bisha B, Hamze M, Kassem I. Critical genomic insights into vancomycin-resistant Enterococcus faecium in Lebanon. Microbiology Spectrum 2025, 13: e00171-25. PMID: 40762484, PMCID: PMC12403557, DOI: 10.1128/spectrum.00171-25.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsBacterial ProteinsCross InfectionDrug Resistance, Multiple, BacterialEnterococcus faeciumGenome, BacterialGenomicsGram-Positive Bacterial InfectionsHumansLebanonMicrobial Sensitivity TestsVancomycinVancomycin ResistanceVancomycin-Resistant EnterococciVirulence FactorsWhole Genome SequencingConceptsVancomycin-resistant <i>Enterococcus faecium</i> (VRSingle nucleotide variantsEnterococcus faecium</i>Hospital-associated lineagesGenomic featuresAntimicrobial resistanceSequence typingClonal disseminationCore genome single nucleotide variantResistance to last-resort antimicrobialsAcquisition of vancomycin resistanceGenetic characteristicsWhole-genome sequencingAntimicrobial resistance genesLevels of antimicrobial resistanceLast-resort antimicrobialsMultidrug-resistant isolatesResistant to vancomycinE-test methodMatrix-assisted laser desorption/ionization time-of-flight mass spectrometryVancomycin-resistant Enterococcus faeciumSpread of antimicrobial resistanceLaser desorption/ionization time-of-flight mass spectrometryMALDI-TOF MSPublic health threat
2020
Over 870 days of successful antibiotic suppression therapy for VRE‐infected left ventricular assist device
Radcliffe C, Grant M. Over 870 days of successful antibiotic suppression therapy for VRE‐infected left ventricular assist device. Journal Of Cardiac Surgery 2020, 35: 1746-1748. PMID: 32557822, DOI: 10.1111/jocs.14690.Peer-Reviewed Case Reports and Technical NotesConceptsVancomycin-resistant Enterococcus faeciumSuppression therapyVentricular assist devicePocket infectionPump exchangeAssist deviceMethicillin-sensitive Staphylococcus aureusAntibiotic suppression therapyLeft ventricular assist deviceUse of daptomycinAdvanced heart failureSymptomatic adverse eventsHeartMate II LVADLong-term suppressionMultidrug-resistant pathogensSurgical drainageAdverse eventsCommon complicationHeart failureClinical challengeInfectionDevice placementTherapyEnterococcus faeciumStaphylococcus aureus
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply