2022
Regulation of glomerulotubular balance. IV. Implication of aquaporin 1 in flow-dependent proximal tubule transport and cell volume
Du Z, Yan Q, Shen E, Weinstein A, Wang T. Regulation of glomerulotubular balance. IV. Implication of aquaporin 1 in flow-dependent proximal tubule transport and cell volume. American Journal Of Physiology. Renal Physiology 2022, 323: f642-f653. PMID: 36108052, PMCID: PMC9705020, DOI: 10.1152/ajprenal.00167.2022.Peer-Reviewed Original ResearchConceptsWater channel aquaporin-1Proximal tubulesKO miceAquaporin-1Water reabsorptionMouse PTNo significant differenceWild-typeTight junctionsRat kidneyAquaporin-1 knockoutSignificant differenceAcid-base parametersKidney proximal tubulesRenal clearance experimentsWT miceKnockout miceUrine flowFlow stimulationFluid absorptionUrine pHClearance experimentsMouse kidneyMiceRats
2014
Acute Kidney Injury
Johnson D, Johnson M. Acute Kidney Injury. 2014, 303-307. DOI: 10.1007/978-0-85729-781-5_31.Peer-Reviewed Original ResearchAcute kidney injuryKidney injuryAdequate renal perfusionIntravascular volume statusNonobstructive causesExcellent diagnostic toolPatient demographicsSerum creatinineBlood lossClinical factorsRenal perfusionVolume statusAnesthetic techniqueToxic nephropathyUrine flowDirect injuryComputed tomographyComprehensive modalityImaging studiesSurgical fieldInjuryPatientsDiagnostic toolNephropathyCreatinine
1989
The influence of perfusate viscosity, RBC deformability and drag on the function of an isolated perfused rat kidney
Sumpio B, Upchurch G, Johnson G. The influence of perfusate viscosity, RBC deformability and drag on the function of an isolated perfused rat kidney. Journal Of Surgical Research 1989, 46: 4-8. PMID: 2915534, DOI: 10.1016/0022-4804(89)90174-1.Peer-Reviewed Original ResearchConceptsRenal functionMean renal arterial pressureRat kidneyKrebs-HCO3 bufferRenal arterial pressureReabsorption of sodiumArterial pressureUrine flowOrgan functionClinical interestHCO3- bufferPerfusate solutionHematocritBlood rheologyFunctional parametersPerfusate viscosityRBC deformabilityKidneyPerfusateDegrees CRBCsDrag-reducing agentsGFRCreatinineAgents
1986
The Role of Ureteral Peristaltic Rate and Bolus Volume on Increasing Urine Flow
Saeki H, Morita T, Weiss R, Miyagawa I. The Role of Ureteral Peristaltic Rate and Bolus Volume on Increasing Urine Flow. Urologia Internationalis 1986, 41: 174-179. PMID: 3750577, DOI: 10.1159/000281192.Peer-Reviewed Original ResearchConceptsUreteral peristaltic ratePeristaltic rateUrine flowBolus volumeTransport of urineUrodynamic parametersMongrel dogsAcute diuresisUreteral peristalsisUrine increasesUrine secretionUreterElectromyogramRate alterationsFlow increasesOliguriaPolyuriaDiuresisConsequent increaseFurosemidePeristalsisSecretionDogsUrine
1984
Beneficial effect of thyroxin on recovery from toxic acute renal failure
Siegel N, Gaudio K, Katz L, Reilly H, Ardito T, Hendler F, Kashgarian M. Beneficial effect of thyroxin on recovery from toxic acute renal failure. Kidney International 1984, 25: 906-911. PMID: 6471672, DOI: 10.1038/ki.1984.108.Peer-Reviewed Original ResearchConceptsToxic acute renal failureAcute renal failureNormal salineRenal failureBeneficial effectsInjected ratsOnly normal salineT4-treated ratsEffect of thyroxinNonspecific systemic effectsT4-treated animalsRenal insultHemodynamic effectsRenal functionRenal injuryControl ratsGlomerular functionUrine flowSimilar doseSystemic effectsEnhanced recoveryPrompt recoveryKidney preparationRatsFENa
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