2020
Dependence of fluorodeoxyglucose (FDG) uptake on cell cycle and dry mass: a single-cell study using a multi-modal radiography platform
Sung Y, Tetrault M, Takahashi K, Ouyang J, Pratx G, Fakhri G, Normandin M. Dependence of fluorodeoxyglucose (FDG) uptake on cell cycle and dry mass: a single-cell study using a multi-modal radiography platform. Scientific Reports 2020, 10: 4280. PMID: 32152343, PMCID: PMC7062696, DOI: 10.1038/s41598-020-59515-0.Peer-Reviewed Original ResearchConceptsCell divisionHeLa cellsDry massM phaseCell dry massCancer compared to normal tissuesCell cycle phasesHouse-keeping proteinsSingle-cell studiesSingle-cell levelIncreased dry massProliferation indexCell cycleG1 phaseProportion of cellsHigher glucose uptakeFluorodeoxyglucose uptakeGlucose uptakeHeLaUptake rate
1993
Studies on regulation of the ascorbic acid transporter in a cell line derived from rabbit non-pigmented ciliary epithelium
Delamere N, Coca-Prados M, Aggarwal S. Studies on regulation of the ascorbic acid transporter in a cell line derived from rabbit non-pigmented ciliary epithelium. Biochimica Et Biophysica Acta 1993, 1149: 102-108. PMID: 8391316, DOI: 10.1016/0005-2736(93)90030-4.Peer-Reviewed Original ResearchConceptsProtein kinase CKinase CAscorbate uptakeCell linesProtein kinase C inhibitorProtein kinase C activatorCultured cell linesPresence of staurosporineKinase C inhibitorAscorbic acid transporterNon-pigmented ciliary epitheliumAscorbate transporterUptake rateAcid transportersC activatorCiliary epitheliumC inhibitorNon-pigmented epithelial cellsPDBu treatmentUptake mechanismEpithelial cellsPDBu effectSodium gradientTransportersCells
1991
Mechanism of mercurial inhibition of sodium-coupled alanine uptake in liver plasma membrane vesicles from Raja erinacea
Sellinger M, Ballatori N, Boyer J. Mechanism of mercurial inhibition of sodium-coupled alanine uptake in liver plasma membrane vesicles from Raja erinacea. Toxicology And Applied Pharmacology 1991, 107: 369-376. PMID: 1994517, DOI: 10.1016/0041-008x(91)90216-2.Peer-Reviewed Original ResearchConceptsDependent alanine uptakePlasma membrane vesiclesMembrane vesiclesAlanine uptakePrimitive vertebratesPlasma membraneTransport proteinsConcentration-dependent mechanismLiver plasma membrane vesiclesMicroM HgCl2Mammalian hepatocytesAlanine carrierSulfhydryl groupsLittle skateMembrane integrityRaja erinaceaDirect interactionVesiclesVesicle integrityMembrane permeabilityMercurial inhibitionUptake rateDose-dependent mannerHgCl2 concentrationsLiver plasma membranes
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