Montelukast improves the changes of cytoskeletal and adaptor proteins of human podocytes by interleukin-13
Ha T, Nam J, Seong S, Saleem M, Park S, Shin J. Montelukast improves the changes of cytoskeletal and adaptor proteins of human podocytes by interleukin-13. Inflammation Research 2017, 66: 793-802. PMID: 28608180, DOI: 10.1007/s00011-017-1058-y.Peer-Reviewed Original ResearchConceptsMinimal-change nephrotic syndromePathogenesis of minimal-change nephrotic syndromeTargeting IL-13IL-13Human podocytesIL-13-induced changesUpregulation of B7Human podocytes in vitroConcentrations of IL-13Slit diaphragmConditionally immortalized podocytesPermeability in vitroAssociated with podocyte dysfunctionPodocytes in vitroConcentration-dependent mannerPotential therapeutic strategyNephrotic syndromeA-actininInterleukin-13Potential cytokinesHigh dosesZO-1Therapeutic strategiesB-cateninMontelukast
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