2020
Rapidly Progressive Soft Tissue Infection of the Upper Extremity With Aeromonas veronii Biovar sobria
Lujan-Hernandez J, Schultz K, Rothkopf D. Rapidly Progressive Soft Tissue Infection of the Upper Extremity With Aeromonas veronii Biovar sobria. The Journal Of Hand Surgery 2020, 45: 1091.e1-1091.e4. PMID: 32238279, DOI: 10.1016/j.jhsa.2020.02.003.Peer-Reviewed Original ResearchConceptsProgressive soft tissue infectionSoft tissue infectionsEarly surgical explorationLife-threatening infectionsAeromonas veronii biovar sobriaAcute clinical managementAntibiotic therapyImmunocompetent individualsAntimicrobial therapyHistory of injuryTissue infectionsSurgical explorationUnusual pathogenAggressive subtypeCase reportHealthy patientsAeromonas veroniiClinical managementCausal agentUpper extremityTherapyInfectionCulture dataAquatic environmentCephalosporins
2013
Reversible epigenetic down-regulation of MHC molecules by devil facial tumour disease illustrates immune escape by a contagious cancer
Siddle H, Kreiss A, Tovar C, Yuen C, Cheng Y, Belov K, Swift K, Pearse A, Hamede R, Jones M, Skjødt K, Woods G, Kaufman J. Reversible epigenetic down-regulation of MHC molecules by devil facial tumour disease illustrates immune escape by a contagious cancer. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 5103-5108. PMID: 23479617, PMCID: PMC3612627, DOI: 10.1073/pnas.1219920110.Peer-Reviewed Original ResearchConceptsDFTD cellsDown-regulation of MHC moleculesMHC class I moleculesClass I moleculesDevil facial tumour diseaseExpression of MHC class I moleculesI moleculesMHC moleculesTumor diseaseMHC class II transactivatorAssociated with up-regulationIn vivoClass II transactivatorTransporter associated with antigen processingLoss of gene expressionCells in vitroDown-regulationAntigen processing pathwayHost immune responseFacial tumour diseaseContagious cancerImmune escapeUnusual pathogenLymphocytic infiltrationT cells
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