2014
Toll-Like Receptor 3 Is Critical for Coxsackievirus B4-Induced Type 1 Diabetes in Female NOD Mice
McCall K, Thuma J, Courreges M, Benencia F, James C, Malgor R, Kantake N, Mudd W, Denlinger N, Nolan B, Wen L, Schwartz F. Toll-Like Receptor 3 Is Critical for Coxsackievirus B4-Induced Type 1 Diabetes in Female NOD Mice. Endocrinology 2014, 156: 453-461. PMID: 25422874, PMCID: PMC4298321, DOI: 10.1210/en.2013-2006.Peer-Reviewed Original ResearchConceptsToll-like receptor 3TLR3 knockout miceWild-type miceNOD miceKnockout miceRole of TLR3Receptor 3Type 1 diabetes mellitusFemale NOD miceProne NOD miceNonobese diabetic (NOD) miceIncidence of diabetesType 1 diabetesViral double-stranded RNAGroup B coxsackievirusesHuman T1DMDiabetes mellitusDiabetic miceMouse modelT1DMTLR3 knockoutUninfected counterpartsUninfected animalsB coxsackievirusesInsulitis
1987
Cytotoxic Factors Secreted by Cells Infected by Human Immunodeficiency Virus Type I
RATNER L, POLMAR S, PAUL N, RUDDLE N. Cytotoxic Factors Secreted by Cells Infected by Human Immunodeficiency Virus Type I. AIDS Research And Human Retroviruses 1987, 3: 147-155. PMID: 3497655, DOI: 10.1089/aid.1987.3.147.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus type IVirus type IMononuclear cellsHIV-1Cytotoxic factorPeripheral blood mononuclear cellsHIV-1 infectionBlood mononuclear cellsHIV-1 replicationTumor necrosis factorCell-derived factorCell linesMonocytoid cell linesType ICytotoxic activityAspects of infectionSystemic manifestationsNecrosis factorUninfected counterpartsVirus replicationConditioned mediaCell killingFibroblast cell lineInfectionMurine fibroblast cell line
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply