2005
Requirement for Tumor Necrosis Factor-Receptor 2 in Alveolar Chemokine Expression Depends upon the Form of the Ligand
Liu J, Zhao M, Xu L, Ramana C, Declercq W, Vandenabeele P, Enelow R. Requirement for Tumor Necrosis Factor-Receptor 2 in Alveolar Chemokine Expression Depends upon the Form of the Ligand. American Journal Of Respiratory Cell And Molecular Biology 2005, 33: 463-469. PMID: 16081883, DOI: 10.1165/rcmb.2005-0204oc.Peer-Reviewed Original ResearchConceptsCD8+ T cellsRespiratory virus infectionsT cellsTNF-R2TNF-alphaAntigen-specific CD8+ T cellsTNF receptorsCD8+ T lymphocytesTumor necrosis factor (TNF)-alphaVirus infectionExpression of TNF-R2Tumor necrosis factor receptor 2TNF receptor 1 expressionT cell responsesMonocyte chemoattractant protein (MCP)-1 expressionTNF-alpha activityEpithelial target cellsTransmembrane TNF-alphaSoluble TNF-alphaMCP-1 expressionBystander inflammationExperimental influenzaT lymphocytesChemokine expressionLung injury
2002
The transmembrane form of TNF-α drives autoantibody production in the absence of CD154: studies using MRL/Mp-Faslpr mice
FUJII T, OKADA M, MIMORI T, CRAFT J. The transmembrane form of TNF-α drives autoantibody production in the absence of CD154: studies using MRL/Mp-Faslpr mice. Clinical & Experimental Immunology 2002, 130: 224-232. PMID: 12390309, PMCID: PMC1906522, DOI: 10.1046/j.1365-2249.2002.01982.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, AntinuclearB-LymphocytesCD40 LigandCell LineCells, CulturedCoculture TechniquesLupus Erythematosus, SystemicLymphocyte ActivationLymphocyte CooperationMembrane ProteinsMiceMice, Inbred MRL lprMice, KnockoutReceptors, Antigen, T-Cell, alpha-betaReceptors, Tumor Necrosis FactorRibonucleoproteins, Small NuclearTh1 CellsTumor Necrosis Factor-alphaConceptsB cell proliferationTh1 linesTNF-alphaB cellsAntibody productionCell proliferationContact-dependent helpMRL/MpB cell helpMHC class IITh1 cell linesB cell activationCD40-CD154Autoantibody productionTh1 cellsCell helpMRL miceMTNF-alphaProliferative responseHigh titresCell activationTNF-R2Class IITransmembrane formMonoclonal antibodies
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